On May 14, 1796, Edward Jenner inoculated a general fatal illness smallpox vaccine in Berkeley, Gloucestershire, England. The vaccine is made from vaccinia, a lighter ailment. Jenner is not the person who first recognized the association between vaccinia and smallpox and even the first doctor who used the vaccinia vaccine for patients who received smallpox vaccine. However, Jenner used scientific methods to carefully record all the stages of his experiment: When the patient recovers, he uses common anti - subtle variation techniques. Mutation refers to the process by which a patient intentionally infects natural strains taken from victims of recently recovered or changed smallpox. This is a very dangerous procedure, but it can cause milder illness. (Variation is not as dangerous as shrinking smallpox.) Culture from China to Turkey has utilized centuries of variability to protect patients from smallpox The vaccinated boy did not infect any form of smallpox after intentionally infected. Learn the behavior of people including their language, belief system, social structure, institution and important products Scientific observations and investigations of subjects usually follow scientific methods: observations, hypotheses, predictions, experiments, analyzes and conclusions Research method to ask questions, collect data, make assumptions, verify hypotheses Preparing a weakened or dead pathogen or a portion of the pathogen structure stimulates the production of antibodies against the pathogen at the time of administration but does not cause serious infection on its own A historical approach to smallpox prevention by intentionally infecting patients with certain diseases Edward Jenner, a British surgeon and naturalist, developed the first vaccine of smallpox vaccine in 1796. Jenner inoculated vaccinia with his gardener's son. And it did not produce smallpox after repeated exposure to infected smallpox material. The first vaccine laid the foundation for the field of immunology. British is the first woman who got a medical degree in the United States, the first woman to receive medical registration in the UK. Black well decided to acquire a medical degree by seeing a friend dying of uterine cancer around 1845. She received a scholarship at Hobart University in Geneva, New York in 1849 and then opened a law firm in New York City. On May 14, 1796, Edward Jenner inoculated a general fatal illness smallpox vaccine in Berkeley, Gloucestershire, England. The vaccine is made from vaccinia, a lighter ailment. Jenner is not the person who first recognized the association between vaccinia and smallpox and even the first doctor who used the vaccinia vaccine for patients who received smallpox vaccine. However, Jenner used scientific methods to carefully record every phase of his experiment: when the patient recovered he used general anti-fluctuation techniques. Mutation refers to the process by which a patient intentionally infects natural strains taken from victims of recently recovered or changed smallpox. This is a very dangerous procedure, but it can cause milder illness. (Variation is not as dangerous as shrinking smallpox.) Culture from China to Turkey has utilized centuries of variability to protect patients from smallpox

Edward Jenner, a British village native from Gloucestershire State, is managing the world's first vaccination as a preventive treatment for smallpox who killed millions of people for centuries. He is still a medical student, but Jenner noticed a milk girl infected with vaccinia. And it made the cow's breast blister and did not discover smallpox. Unlike smallpox, smallpox causes severe rash and dangerous fever in humans, vaccinia makes these women have little symptoms. On May 14, 1796, Jenner took liquid out of the vaccinia blister and scraped it off the skin of an eight-year old boy James Phipps. The blisters increased on the spot, but James soon recovered. On July 1, Jenner received vaccination again for this boy, but this time there was no disease with smallpox. The vaccine was very successful. Doctors throughout Europe quickly adopted Jenner's innovative technology, resulting in a sharp decline in the number of new generations of patients with devastating diseases From the 19th century to the 20th century, scientists following the Jenner model developed new vaccines against various deadly diseases such as polio, pertussis, measles, tetanus, yellow fever, typhoid fever, hepatitis B, A more sophisticated smallpox vaccine has also been developed and the 1970 international vaccination program like the World Health Organization (WHO) vaccine eliminated smallpox worldwide. Edward Jenner, a British surgeon and naturalist, developed the first vaccine of smallpox vaccine in 1796. Jenner inoculated vaccinia with his gardener's son. And it was unable to produce smallpox after repeated exposure to infected smallpox material. The first vaccine laid the foundation for the field of immunology. British is the first woman who got a medical degree in the United States, the first woman to receive medical registration in the UK. Black well decided to acquire a medical degree by seeing a friend dying of uterine cancer around 1845. She received a scholarship at Hobart University in Geneva, New York in 1849 and then opened a law firm in New York City. On May 14, 1796, Edward Jenner inoculated a general fatal illness smallpox vaccine in Berkeley, Gloucestershire, England. The vaccine is made from vaccinia, a lighter ailment. Jenner is not the person who first recognized the association between vaccinia and smallpox and even the first doctor who used the vaccinia vaccine for patients who received smallpox vaccine. However, Jenner used scientific methods to carefully document all the stages of his experiment: when the patient recovered he used general anti - fluctuation techniques. Mutation refers to the process by which a patient intentionally infects natural strains taken from victims of recently recovered or changed smallpox. This is a very dangerous procedure, but it can cause milder illness. (Variation is not as dangerous as shrinking smallpox.) Culture from China to Turkey has utilized centuries of variability to protect patients from smallpox

Smallpox is currently eradicated for centuries, one of the world's most terrible epidemics. The World Health Organization (WHO) promoted vaccination programs globally and eliminated the disease from the world. With this promotion, the last natural case in the world occurred about 40 years ago. Once eradicated, the general public stops routine or forced vaccination and I believe there is no longer any need to prevent the disease. The world has been eradicated but there are still two R & D laboratories in Russia and the United States. The origin of smallpox is not clear. Smallpox is thought to date back to the Egyptian empire around the 3 rd century BC (based on rashes like small pox found in the three mummies). The earliest written explanation of diseases that are clearly similar to smallpox appeared in China during the 4th century AD (ordinary period). Early written explanations appeared in India in the 7th century and in small Asia in the 10th century. One of the first ways to control the spread of smallpox is to use variations. Named for the virus that causes smallpox (Variola virus), the mutation is the process by which a substance derived from smallpox (pustule) is given to a person who has never experienced smallpox. This can be done by rubbing the material on the arm or by sucking through the nose. With these two types of mutations, people often continue to develop symptoms associated with smallpox such as fever and rashes. Smallpox is a very serious disease caused by a virus called Baliola virus (eg vair-ee-OH-luh). The name of smallpox comes from blisters (or acne scars) filled with pus formed during the disease. These names sound similar, but smallpox has nothing to do with varicella. It is a lighter illness caused by various viruses. You have heard about smallpox, you want to know what it is, or you or someone you know can get it. Some people are worried that bacteria causing smallpox may spread and be used as weapons. This is difficult for everyone. Currently there are no cases of smallpox in the United States. In fact, the last case of smallpox in the United States occurred in 1949, the last case in the world occurred in 1977. At the time of eradication, chickenpox is often confused with smallpox. There are several ways to distinguish varicella and smallpox. Unlike smallpox, chickenpox usually does not affect the palms or soles of the feet. In addition, due to transient changes in the pustules, varicella pustules vary in size. As the virus effect progresses more evenly, the pustules of smallpox are about the same size. In the evaluation of cases suspected of smallpox, there are various examination methods for detecting varicella

In biological weapons, smallpox is a bad child so far for all people. "35 million Aztecs died in the next two years when Hernando Cortés arrived in the country to infect Azteca's Indian community in 1520. In 1763 the US Pontiac's Henry Bush cow uprising In between, a blanket infected with smallpox was sent to thousands of murdered Native Americans; British Army Commander in North America Sir Geoffrey Amherst used the same technology in New England and the results were the same (P. Causes and effects of smallpox are caused by smallpox virus that occurred in humans thousands of years ago. Smallpox is a special, infectious, highly contagious and highly febrile illness that only humans can spread. It will be caused by viruses in the air current, eventually spreading from person to person. Smallpox has changed from a mild form without skin symptoms to bleeding in a very lethal form. British doctor, Edward Jenner, found a precautionary measure Smallpox inoculation of smallpox virus (Jenner has not developed a vaccination program using vaccinia virus). Immunization is dangerous. Due to the use of live virus, the patient may develop smallpox and die. Patients can also use smallpox to infect others. It is one. Immunization has previously been proven to be effective in suppressing the occurrence of smallpox in Boston during the 1720s. When he was a surgeon at a hospital in Boston, at the beginning of the war, John Warren (brother of Joseph Warren) vaccinated new recruits. Inoculation of smallpox by the end of the 18 th century is a common prevention method in Europe. Smallpox vaccination means the introduction of smallpox pus under the patient's skin. Shortly thereafter, immunization was conducted in North America (more effective, less dangerous). However, the epidemic of smallpox continues to affect the population. Montreal received particularly intense blows. The epidemic of 1885 was particularly prominent and its size encouraged municipalities to vaccinate, but medical advice was divided into vaccination and anti-vaccination camps, and the former criticized spreading the disease. People are afraid to refuse vaccination. A riot occurred in the city on September 18, 1885. Dismantled the vaccination poster and was fired official medical vaccinator, city hall, pharmacy, municipality's residence

Previously it was expressed as a result of behaviors taken mainly by the World Health Organization (WHO) and a small group of other major players, but the recent interpretation on the eradication of smallpox is based on this international cooperation and its participants It deals from different viewpoints. Current historians are studying this outcome. It depends not only on mutual understanding about the need to end smallpox but also on international and regional socio-political forces. In a 1993 article "Smallpox: Appearance, Global Expansion and Eradication", Frank Finner, a worldwide known virologist and chairman of the global smallpox eradication committee, explained. Traditionally, health care has been recognized as an important determinant of general physical and mental health and the well-being of people all over the world. An example of this is the fact that smallpox was eradicated globally in 1980 and the World Health Organization (WHO) said that it is the first disease in human history to be completely eliminated by intentional medical intervention I declared. The provision of modern health care depends on interdisciplinary team of trained professionals and semi-experts. This includes medicine, psychology, physical therapy, nursing, dental, midwifery and allied health experts, as well as public health professionals, community health workers and support staff, which are systematically personal and population Provide people based on. Prevention, treatment and rehabilitation care services The Public Health Initiative has improved and extended the lives of millions of people around the world. In the last century, public health experts and organizations established global HIV / AIDS alliances in Africa by eliminating smallpox worldwide, establishing international nuclear test ban and environmental agreement, establishing an international I lengthened the average life expectancy by 30 years. The first large-scale smallpox eradication work began in 1950 with the aim of eliminating American smallpox. In 1958, the World Health Assembly passed a resolution calling for global eradication of smallpox. In some countries planning to eradicate smallpox is planned, but there is no coordinated infrastructure. Due to insufficient supply of vaccines and limited resources, many plans are shaken. In the United States of the 19th century, there were generally more toxic smallpox being the main species, but only two major outbreaks occurred between 1900 and 1925. By contrast, in the 20th century the mild form of small pox It only appeared in the 1930s. There have been no smallpox cases in the United States since 1949, but in developing countries this disease is still a serious problem.

New England Aboriginal New England Aboriginal people first felt the influence of smallpox and other diseases in the first decade of the 16th century. Just after John Cabot explored the coast in 1498. By 1504, French and Portuguese continued fishing trips and began spreading the disease. However, in 1616 and 1617, numerous people of indigenous peoples were murdered. Diseases such as varicella, cholera, plague, tuberculosis, etc. were first introduced to New England. In the UK, in the late 1790s, physician Edward Jenner discovered how to vaccinate people with smallpox vaccine. About 190 years later in 1980, it was declared that smallpox was eradicated (Edward Jenner). Today, humans keep track of Jenner's footprints and continue working to treat and eradicate diseases threatening people around the world. Unfortunately, vaccines and antibiotics are not necessarily effective, and scientists need to find new ways to treat diseases that have not yet cured, such as Alzheimer's disease, Parkinson's disease, diabetes. On May 14, 1796, Edward Jenner inoculated a general fatal illness smallpox vaccine at Berkeley, Gloucestershire, England. The vaccine is made from vaccinia, a lighter illness. Jenner did not initially recognize the association between vaccinia and smallpox and it was not even the first physician to use the vaccinia vaccine for patients who received vaccinia smallpox. However, Jenner used scientific methods to carefully document all the stages of his experiment: when the patient recovered he used general anti-fluctuation techniques. Mutation refers to the process by which a patient deliberately infects a natural strain taken from a recently recovered or altered smallpox victim. This is a very dangerous procedure, but it can cause a more mild form of the disease. (Variation is not as dangerous as shrinking smallpox.) Culture from China to Turkey has utilized centuries of variation to protect patients from smallpox The arrival time of smallpox in Europe and Southwest Asia is not clear. Smallpox is not explicitly stated in the Old Testament, the New Testament, or in Greek and Roman literature. Although some people have discovered that the plague of Athens said to be derived from "Ethiopia" and Egypt, or that Cartago surrounded the sacred city of Syracuse in 396 BC, many scholars believe that this disease is like smallpox Pocladi once existed in the Mediterranean in his life, and he will not be explained by these people. In the ninth century, Persian physician Rhazes provided one of the most descriptive explanations of smallpox, and in his Kitab fi al-jadari wa-al-hasbah (smallpox and measles book) It was the first person to distinguish between measles and varicella. Man. Smallpox occurred in most parts of Europe in the 16th century.

Author's view of the book is unique. According to most histories, small flowers are not the role of the hero, they do not play a small role. In my opinion, smallpox is a major factor during the revolutionary warfare, Farn focuses on several important areas, see the spread of the epidemic as well as soldiers and its suppression against settlers can do. When choosing the victim, smallpox did not play favorite. Regardless of whether it is a child or an elderly, smallpox has destroyed hundreds of thousands of lives in the colony for eight years. However, until then the smallpox has reached the Americas. Native Americans have little resistance to smallpox in Europe, measles, malaria, sexually transmitted diseases, as well as common colds. Beginning in December 1518, the disease hit Ispaniola followed by Puerto Rico, Jamaica and Cuba. By October 1520, smallpox arrived at Tenoktitran. The successor of Moctezuma died of smallpox in early December. And a lot of dead people confused the town. Still, it is difficult for the Spaniard to conquer the Aztecs. Before Tenoktitran surrendered in August 1521, he kept fighting for 80 days. Spanish guns and artillery are not decisive. About 100,000 troops and mobile fleet provided by Trascarance wins the Spaniards There was no reliable explanation of smallpox disease in the Americas before the Europeans explored the western in the 15th century. Smallpox was brought to Hispaniola Island in the Caribbean Sea in 1509 and entered the mainland in 1520. At that time, settlers from Spanish Hispaniola arrived in Mexico and brought smallpox. Smallpox destroyed indigenous peoples of American Indians and was an important element for the Spaniard to conquer Azteca and Inca. In 1633 he settled on the east coast of North America in Plymouth, Massachusetts. Along with that, the devastating occurrence of smallpox in the Native American population and the subsequent outbreak of native colonists occurred. The mortality rate between native American outbreaks was as high as 80-90%. Smallpox was once again introduced to Australia in 1789 and 1829. Although this disease has never spread in the African continent, it has become a major cause of death among indigenous peoples between 1780 and 1870. Smallpox came to North America in the early 17th century. People have symptoms of high fever, chills, terrible back pain and rash. Starting in the northeast, smallpox eliminated the entire indigenous population. Over 70% of the native American population has declined. In 1721, 844 of 5,889 Boston people suffering from smallpox died here. Philadelphia was once the capital of the country and the busiest harbor. Yellow fever refugees in the Caribbean islands are infected with the virus in the wet summer. Yellow fever causes skin yellowing, fever and hemorrhagic vomiting. 5000 people died and 17,000 people fled from the city

About 3000 years, smallpox has devastated the four corners of the world and plagued it. Indeed, from the 17th century to the 18th century, the most infectious disease in the western area was considered high and in the United States it was an incredible mortality rate of 90%. Until 1796, British surgeon Edward Jenner received vaccinated smallpox vaccine, and the world saw this kind of catastrophic viral relief. However, even with this vaccination, the world continues to witness the deaths of viruses and vaccines. A study of the history of smallpox vaccination found that the actual viruses used for vaccination are genetically distinct vaccinia viruses belonging to the same family as smallpox (small) and vaccinia virus. Although the origin of vaccinia virus is not clear, it is believed to have occurred in the 19th century. Immunization and preventive measures by the Alliance and Federal Health Department prevented the occurrence of smallpox during war and prevented large outbreaks. Successful vaccination of soldiers during the Civil War led to vaccination of civilians after the war and further helped to control this serious disease. The first human vaccine against viruses is based on the use of weaker or attenuated viruses to generate immunity. Smallpox vaccine uses vaccinia, a poxvirus similar to smallpox, for prevention, but it usually does not cause serious illness. Rabies is the first virus attenuated in the laboratory to produce human vaccines. Vaccines are made in several ways. Inactivated or killed organisms or viruses, inactivated toxins (which are not bacteria that cause the disease itself, but bacteria that cause diseased toxins, bacterial properties that are not disease causing toxins), live viruses that are attenuated (weakened or altered to avoid diseases) A disease) or a simple fragment of a pathogen (which includes subunits and conjugate vaccines)

Impact of smallpox on the new world Since the era of hunter gatherers, humans have always been important for the transport and movement of Homo sapiens. Since then, humans have used a variety of means of transport (eg, living in the case of hunter gatherers, spreading religious beliefs, looking for valuable minerals and spices). Most of these travelers are not aware that diseases are moving with them. In this article I will investigate the spread of diseased smallpox. When European explorers reached the New World in the era of exploration, they have brought many different kinds of diseases that have not yet emerged in the new world: smallpox, influenza, measles, malaria, varicella and yellow fever . These diseases spread as part of Colombian exchange and kill millions of people. In fact, some historians believe that 90% of the new world is dying from the spread of diseases in Europe. The indigenous peoples of the New World have never been exposed to these diseases, so they are not immunocompetent and are vulnerable to the fatal effects of this disease. One of the most important diseases in Europe is smallpox. And it is said to have the greatest impact on the indigenous people of the New World. For example, it is reported that the Aztecs of Tenoktitran experienced the spread of large-scale smallpox from September to November 1520. Infectious diseases brought about by Spaniards include smallpox, measles, and influenza. These diseases, like typhoid fever and yellow fever, had a major influence on Maya's population. Old world diseases brought by the Spaniards and old world diseases in which the people of the New World did not resist; they were determinants of conquest; they destroyed the population before fighting or even before fighting. It is estimated that 90% of indigenous peoples were eliminated by disease in the first century of contact in Europe In the nineteenth century many endemic diseases and epidemics have plagued the coastal areas of Benin, but they have various ways to influence Europeans and indigenous peoples. If smallpox is not like malaria, sleep disorder, yellow fever, it is not a main concern, because it mainly affects indigenous peoples. Therefore, Pierre Bouche (1885, p. 206-207) observed that he did not know the European who escaped malaria during the visit to the coast, but he saw that smallpox was "badly damaged" It was the root cause of the problem. Blacks said, "There were only 1,300 people murdered in Agu in 1873, and six of 18 blacks carried from Sao Tome on the end of 1875 stationed in Utada's Portuguese fortifications to prevent illness or Focus on eradication

In prehistoric times of the smallpox century AD, the disease was not known, but it is said to have been found in the mummy of Pharaoh Ramses V in Egypt who died in 1157 BC (Henderson, Fenner, Arita, Ladnyi , 1988). p 209-210). There is evidence that pustules and rashes found in mummies are similar to those described for variola virus. Some of the ideas on where the disease comes from are unknown, and the origin of the disease is unknown. The history of smallpox has spread to prehistoric times, and this disease may have occurred in humans in 10,000 BC. The earliest reliable evidence of smallpox was found in Egyptian mummies that died about 3,000 years ago. Especially small indigenous peoples of small-scale smallpox such as the Americas and Australia were rapidly destroyed and weakened by smallpox (and other introduced diseases) during the initial foreign period, so smallpox is great in world history Influenced. Conquest and colonization opened the door. In the 18th century, about 400,000 Europeans died each year due to the disease, including five reigning monarchs, one third of blindness occurred. 20 to 60% of all infected people and more than 80% of infected children have died of this disease Cholera, plague, smallpox, influenza are among the most brutal murderers in human history. These diseases are occurring across national boundaries and have been correctly defined as smallpox, in particular that has caused 300 to 500 million deaths in the 12000 years history. Since its first confirmed in the Democratic Republic of Congo in 1976, HIV / AIDS has proved to be a worldwide outbreak since more than 36 million have died since 1981. Currently there are 30 million to 35 million people infected with HIV, most of which are infected with HIV. In sub-Saharan Africa, 5% of the population is infected and about 21 million people are infected. As awareness rises, new treatments have been developed to make HIV more manageable, and many infected people continue to lead a productive life. Between 2005 and 2012, the worldwide annual deaths from HIV / AIDS decreased from 2.2 million to 1.6 million.

When he was a child, he was a disciple surgeon for nine years and it was a place where I observed and studied surgeons throughout my life. From there he went to St. George's Hospital in London to study anatomy and surgery. From there he returned to his hometown and continued medical practice. In 1978, a smallpox attack hit Gloucestershire, and he observed that the patient he worked with the cow had no signs close to those who did not work with the cow Did. British surgeon and naturalist Edward Jenner developed the first vaccine, smallpox vaccine in 1796. . Jenner inoculated vaccinia with his gardener's son. This first vaccine has laid the foundation for the field of immunology. British are the first women who got a medical degree in the United States and are the first women registered in the UK and this list lists all the doctors licensed in that country. After meeting with a friend who died of uterine cancer around 1845, Blackwell decided to acquire her medical degree. She received a scholarship at Hobart University in Geneva, New York in 1849 and then opened a law firm in New York City. The history of smallpox and vaccination was recorded as early as 1122 BC. (Riedel "smallpox is the origin of disease"). Human victory for this terrible disease was initiated by a British doctor named Edward Jenner. Through observation and experimentation, Jenner creates a program known as immunization. (Ridel "Edward Jenner"). During the next two centuries the vaccine will be used to stop small spread of smallpox worldwide. After the global vaccination campaign succeeded On May 14, 1796, Edward Jenner inoculated a general fatal illness smallpox vaccine at Berkeley, Gloucestershire, England. The vaccine is made from vaccinia, a lighter illness. Jenner did not initially recognize the association between vaccinia and smallpox and it was not even the first physician to use the vaccinia vaccine for patients who received vaccinia smallpox. However, Jenner used scientific methods to carefully document all the stages of his experiment: when the patient recovered he used general anti-fluctuation techniques. Mutation refers to the process by which a patient deliberately infects a natural strain taken from a recently recovered or altered smallpox victim. This is a very dangerous procedure, but it can cause a more mild form of the disease. (Variation is not as dangerous as shrinking smallpox.) Culture from China to Turkey has utilized centuries of variation to protect patients from smallpox

The role of smallpox vaccine in the prevention and treatment of geranium and smallpox has deprived many lives since the Middle Ages. But it has now been fundamentally eradicated, partly because of the highly effective vaccine. This vaccine saved the lives of thousands of people and eliminated this disease in the history of mankind. Although this miracle vaccine can greatly reduce the influence of smallpox, it can prevent disease from being fatal. This vaccine is also the only known anti-small method and it will be the only way that humans can resist this deadly and devastating disease before it is discovered. Smallpox is a highly contagious disease caused by the smallpox virus. Smallpox has four subspecies, smallpox primarily small, smallpox, bleeding, malignant, the most common are smallpox, smallpox small. Symptoms of this disease include bleeding, blindness, low back pain, and vomiting, which usually occur immediately after the incubation period of 12 to 17 days. The virus begins to attack skin cells and eventually leads to the occurrence of pimples covering the whole body. As the disease progresses, acne is filled with pus or combined. This combination separates the sheet from the bottom skin and the top skin. This disease can spread easily using air route (cough, sneeze, breathing), contaminated bedding, clothing, other cloths. Smallpox is caused by two viruses, Variola major and Variola minor. At the end of the century there were smallpox vaccines in colonies of Europe, America, Spain. The Latin name for this disease is Variola Vera. Words come from varius or varus. In the UK, this disease was first called "pox" or "red cockroach." Smallpox is also fixed in small blood vessels of the skin as well as mouth and throat. Symptoms of smallpox are skin rash and liquid-filled blisters. Smallpox is an ancient disease caused by the smallpox virus. This virus exists in two main forms: a Variola major with historically about 30% mortality and a Variola minor with a mortality rate of about 1%. Smallpox is transmitted primarily by direct or indirect contact with airway droplets of the infected person. The main spontaneous onset of smallpox begins with mucosal infection of the upper respiratory tract system, then invades the bloodstream, eventually invades the skin, shows classical signs of smallpox pustules, and the patient becomes infectious Indicates that it has become. May cause death due to toxins in the blood, thrombosis and septic shock

The story of the vaccine does not begin with the first vaccine - Edward Jenner uses the vaccinia pustular material to provide ceiling protection. Instead, it begins with a long history of the early use of smallpox substances to provide immunity to human infections, especially diseases. There is evidence that China used smallpox inoculation (or variant of smallpox) as early as the year 1000 AD. It also took place in Africa and Turkey before spreading to Europe and the Americas. Edward Jenner's innovation began with the successful use of vaccinia to develop immunity against smallpox in 1796 and soon this method became widely available. His method experienced medical and technical changes over the next 200 years, which ultimately led to the elimination of smallpox. The 1885 rabies vaccine of Louis Pasteur is the second vaccine to affect human diseases. After that, it rapidly developed at the dawn of bacteriology. Anti-leukemia and vaccines to prevent diphtheria, tetanus, anthrax, cholera, plague, typhoid fever, tuberculosis, etc. were developed in the 1930's. Mid-20th century was an active period of research and development of vaccines. The way to cultivate the virus in the laboratory has resulted in rapid discovery and innovation, including the development of vaccines for polio. Researchers are targeting other common childhood diseases like measles, mumps, rubella, and vaccines for these diseases greatly reduce the burden of the disease. Currently, innovative technology promotes vaccine research, recombinant DNA technology and new delivery technology are changing scientists to a new direction. Disease targets are expanding and several vaccine studies have begun to focus on noninfectious diseases such as intoxication and allergies. These schedules include not only the science behind the vaccine but also the early harassment of the smallpox variator (see the threat of the famous minister described in the Boston smallpox outbreak of 1731) to the establishment of a vaccination mission It also includes the cultural aspects of vaccination. Influence of war and social unrest on vaccine preventable diseases. Edward Jenner, Louis Pasteur, Maurice Hilleman, pioneers of vaccine development also gained special attention. This timeline category contains almost all entries for a specific topic timeline. Several entries have been omitted to broadly show the overview. The schedule of the implementation plan is organized annually. Figure 8 is a graphical representation of the schedule of a complete implementation plan. The section after the figure shows the outline and table of elements and elements of the elementary school grade 0 grade (Table 4), primary grade 1 grade (Table 5), 2 nd grade 5 grade plan. (Table 6). 0 Year (2015-2016): Baseline and Recognition: University of South Florida Sarasota - Manatee's Incredi-Bull Critical Thinking The main goal of QEP 0 years is to build a strong baseline database Includes use of existing and new evaluations. Experimentally improve important columns of data thinking, continue to build teacher's knowledge and skills related to critical thinking education, deepen understanding of QEP topics including critical thought promises and knowledge standards. Assign FTE. management An article about the president and a historical timetable detail the important issues and achievements of all the presidents of the United States of America. The next video will provide you with other important facts and dates for all US presidential personal and political lives. The format of the next fact file shows the overview of President Glover Cleveland and the historical timeline of important events and achievements during president inauguration. President Glover Cleveland 's timeline details a series of important historical events and outcomes that have had a major impact on the history of the United States in chronological order. I got into a panic in 1893. Panic in 1893 continued from May until N

To distinguish the symptoms of Variola minor and Major is a very lethal disease and many symptoms are accompanied. The two main forms of smallpox, Variola major and Variola minor, show many similar symptoms at the same time. However, there are mainly several different symptoms, slightly not. These include bleeding and internal and external bleeding. These extreme symptoms are the more common cause of the two forms, the mortality rate is 30%, the mild cause is only 1%. Smallpox is a highly contagious disease caused by the smallpox virus. Smallpox has four subspecies, smallpox primarily small, smallpox, bleeding, malignant, the most common are smallpox, smallpox small. Symptoms of this disease include bleeding, blindness, low back pain, and vomiting, which usually occur immediately after the incubation period of 12 to 17 days. The virus begins to attack skin cells and eventually leads to the occurrence of pimples covering the whole body. As the disease progresses, acne is filled with pus or combined. This combination separates the sheet from the bottom skin and the top skin. This disease can spread easily using air route (cough, sneeze, breathing), contaminated bedding, clothing, other cloths. Smallpox is caused by two viruses, Variola major and Variola minor. At the end of the century there were smallpox vaccines in colonies of Europe, America, Spain. The Latin name for this disease is Variola Vera. Words come from varius or varus. In the UK, this disease was first called "pox" or "red cockroach." Smallpox is also fixed in small blood vessels of the skin as well as mouth and throat. Symptoms of smallpox are skin rash and liquid-filled blisters. Smallpox is an ancient disease caused by the smallpox virus. This virus exists in two main forms: a Variola major with historically about 30% mortality and a Variola minor with a mortality rate of about 1%. Smallpox is transmitted primarily by direct or indirect contact with airway droplets of the infected person. The main spontaneous onset of smallpox begins with mucosal infection of the upper respiratory tract system, then invades the bloodstream, eventually invades the skin, shows classical signs of smallpox pustules, and the patient becomes infectious Indicates that it has become. May cause death due to toxins in the blood, thrombosis and septic shock

Variola major: its symptoms and possible use for bioterrorism Smallpox is a virus declared by the World Health Organization (WHO) in 1990. It has long been considered as one of the most dangerous threats to humanity, but it has been eliminated by the coordinated efforts of several international organizations. Its role, especially the role of bleeding strains, is comparable to the effects of Zaire Ebola, Lassa hemorrhagic fever and Marburg virus. Smallpox is a highly contagious disease caused by the smallpox virus. Smallpox has four subspecies, smallpox primarily small, smallpox, bleeding, malignant, the most common are smallpox, smallpox small. Symptoms of this disease include bleeding, blindness, low back pain, and vomiting, which usually occur immediately after the incubation period of 12 to 17 days. The virus begins to attack skin cells and eventually leads to the occurrence of pimples covering the whole body. As the disease progresses, acne is filled with pus or combined. This combination separates the sheet from the bottom skin and the top skin. This disease can spread easily using air route (cough, sneeze, breathing), contaminated bedding, clothing, other cloths. Smallpox is an ancient disease caused by the smallpox virus. This virus exists in two main forms: a Variola major with historically about 30% mortality and a Variola minor with a mortality rate of about 1%. Smallpox is transmitted primarily by direct or indirect contact with airway droplets of the infected person. The main spontaneous onset of smallpox begins with mucosal infection of the upper respiratory tract system, then invades the bloodstream, eventually invades the skin, shows classical signs of smallpox pustules, and the patient becomes infectious Indicates that it has become. May cause death due to toxins in the blood, thrombosis and septic shock Although smallpox may have disappeared, the smallpox virus remains controversial and remains safe in the laboratories of Russia and the United States. Concern was expressed about the prospect of smallpox as a biotero weapon. Considering that people are no longer vaccinated against smallpox, the impact of such events can be devastating. This virus is most likely to originate in primates in Africa, has infected humans for nearly a century and is spreading all over the world. Untreated HIV slowly destroys the immune system of the infected person and causes excessive opportunistic infections and cancer called acquired immune deficiency syndrome (AIDS). This is the first article in the 4th series exploring how infection affects our culture and evolution and how we influence them.

Since the first governor of the Massachusetts colony in John Winthrop, the American epidemic is that the Americans are trying to create a utopian society (40 years old Brinkley), so the United States should see himself as a "mountain town" It was announced that. Winthrop America as the Kingdom of God, this place will not have trouble repeated in the rest of Europe and the rest of the world. This ideal is also appreciated by the American society, but Americans can not accept the idea that the epidemic may attack their own country. Several examples will help explain how these factors are configured for a particular epidemic. America's epidemic of the 18th century is the most annoying thing of the 1730s when it hit the village of New England in the north, small towns and diphtheria vogue. By exceeding the destiny of rural New Hampshire and Massachusetts states, the epidemic has had an unusual influence for children and their families. From the epidemiological point of view of diphtheria epidemics - repeatedly fears like New England colonies repeatedly cause smallpox epidemics - is a phenomenon caused by isolated isolation and weak. Epidemics in London are epidemic in New England and can become a very deadly disease: "In some towns, nearly half of children's deaths, sometimes people are actually colonized I am afraid to destroy it. " Aboriginal people in north North America also have a similar effect. During 1616, along the coast of New England in 1618, the epidemic deprived 75% of the population of indigenous peoples. In the 1630's, at least half of Huron easy Iroquoids around the Great Lakes died of smallpox. In addition to smallpox, other diseases occurring in Europe caused severe damage to North American native people. These diseases include measles, scarlet fever, varicella, whooping cough, plague, malaria, dysentery, cholera, yellow fever and influenza. In most cases, these diseases effectively kill the native Americans more than European explosives. When Europeans began arriving on the American coast, they led to epidemics leading to one of the biggest population imbalances in human history. Before arriving in Europe, there were no diseases such as smallpox, measles, yellow fever etc in these parts of the world. These diseases have never been touched and indigenous people do not have the antibodies necessary to fight infections. Europeans continue to explore new areas Christopher Columbus arrived in America as a starting point in the United States in 1492 and touched a different community, so the epidemic Aboriginal population greatly for the next 400 years Decrease.

Three of the Spaniards beat Aztecs, horses, gunpowder, and sickness. Before the Spaniards came to the New World, the Native American did not have horses. Ma has long been used in war in Europe. This horse gives a higher perspective to the owner and is clearly advantageous to chase the retreating enemy. When combined with a spear, the installed warrior is superior to the club infantry. Aztecs also do not know how to think of Spanish horses, so they also have shocking value. Explosive technology helps to make Aztec fortress debris. The first gun and cannon were loaded slowly, some were unreliable. However, they emit a lot of noise to generate smoke, so it is possible that they will confuse unfamiliar enemies. Aztec weapons can be loaded faster, but those bows and obsidian knives do not match the Spanish armor. Like horses, gunpowder technology is worthy of impact, weakening the morale of more Aztecs. The last factor of Aztec failures was disease. This factor is not intentionally introduced by Spanish people. However, smallpox and diphtheria ruin indigenous peoples throughout Africa. The fact that the prayers of the local saints did not cure the disease also helped to weaken the society of Aztec. This disease made it possible for a handful of Spaniards to defeat the empire that has existed for centuries. Three factors that Spain repel Azteca were illness, excellent weapons, and Aztec religion. First, the Europeans infected the smallpox virus to the native American who had not been immune to the disease without knowing it. Smallpox killed thousands of native Americans, which weakened the Aztec empire and caused political and social instability. Next, Hernan Cortes and his men have excellent weapons. The Spaniards have steel weapons, cannons and horses; these benefits helped them to beat the larger Aztec armies. Third, the Aztec religion made it possible for Cortes to infiltrate the Aztec government. Emperor Mokutezuma of Aztec (sometimes spelled with Montezuma) thought that Cortes was Quetzalcoatl of Azteca (or at least sent by him). Therefore, he welcomes the Spaniard rather than oppose them. Entering Tenoktitran (the capital of Azteca), Cortez treated the prisoners of Moctezuma as rulers. The Aztec civilization suddenly ended by Hernandokorte and his invasion forces between 1519 and 1521. The main reason for Aztec failures was the introduction of smallpox from Spain; millions of Aztecs died in the last month of resistance in 1521 and the first 50 years of Spanish colonialism. The Spaniards quickly annihilated the empire system like the Mexican empire and ritual, but the life of Aztec farmers was hardly interrupted during the colonial period. The Nahuatl language is still an important language in rural Mexico and many aspects of today's traditional village custom can be traced back to the Aztec era. Three factors that Spain repel Azteca were illness, excellent weapons, and Aztec religion. First, the Europeans infected the smallpox virus to the native American who had not been immune to the disease without knowing it. Smallpox killed thousands of native Americans, which weakened the Aztec empire and caused political and social instability. Third, the Aztec religion made it possible for Cortes to infiltrate the Aztec government. Emperor Mokutezuma of Aztec (sometimes spelled with Montezuma) thought that Cortes was Quetzalcoatl of Azteca (or at least sent by him). Therefore, he welcomes the Spaniard rather than oppose them. Entering Tenoktitran (the capital of Azteca), Cortez treated the prisoners of Moctezuma as rulers.

Epidemiology and Disease Management around the 1940's Andrea Barrett's "The Heat of the Ship" got a historically new approach to ship and disease in the mid-19th century. We are suffering from diseases such as dysentery, blisters, the heat of the ship. Another disease mentioned in the novel is huge, it seems to be the same as or similar to dengue fever and kara azar. Let me briefly explain these issues before moving on to the story role. Dysentery is caused by bacteria of Shigella spp. It can not meet national health themes like ordinary infectious diseases. In the 1930s and 1840s there were three major infectious diseases from 1831 to 1833, including two epidemics of influenza and cholera. The main epidemic diseases such as influenza, typhus, typhoid, cholera etc. As F. H. Garrison observed, the epidemics of the 18 th century was "more isolated and isolated than before," and in the early nineteenth century diseases such as diphtheria and influenza were greatly reduced. Smallpox is a tragedy in the 18th century and seems to be managed by the new immunization law. Then in the mid - 1920s the UK saw a serious outbreak of smallpox and typhoid, and it is expected that plague will become turbulent over the next 20 years. Historically, terrible epidemics have occurred over and over again. Several pandemics, such as smallpox, pest, influenza, etc. exist in history. Smallpox was eradicated in the world in 1980. In the 18 th century, the world's major trade route, several destructive cholera epidemics caused enormous infections. For example, one third to one half of people died of black death that hit Europe in 1347. In many towns, this pathological generation caught the progress of civilization. What is fashion? This is short term, usually in weeks, the spread of infection rapidly. Which ratio constitutes a fashion? In case of meningitis, there are more than 15 cases per 100,000 people in 2 weeks. Our overall murder rate is less than 5 people per 100,000 people a year, the kill rate of certain guns is even lower. Please select a baseline. The average murder rate of this country since 1910 is 86. This is 26 years old since the beginning of this century. This decade is 68 years old. What is a baseline? Whichever baseline you select, there is no fashion. This is a fake. However, most people definitely think this is a fashion. Pew Research Center is tracking this. Below is the chart of the survey conducted in 2013.

Little Pox Magazine April 22, 2005 - Since I have had a long week, I decided to write this article on an online magazine. After doing several papers, quizzes, and 40 hours of work, I got a bit bad weather. But most of us think this is because I am not asleep. But do not worry because I'm planning to make up for it on the weekend. But tonight I decided to go to a party and go to my apartment. Until then I will lie down drinking aspirin and going out. Small Pox & lt; Tab / & gt; Smallpox Virus & lt; Tab / & gt; Small Pox Vaccine is not manufactured or registered for use in Australia. Over 20 years ago commercial production of small pox vaccines in the world ceased. Edward Jenner found the first vaccine, the small pox vaccine so far. This vaccination resulted in effective protection of the disease by stimulating the production of antibodies against diphtheria toxin, a toxigenic strain of acne diphtheria, clostridium difficile. In Australia, the diphtheria vaccine exists in the form of DTP (diphtheria, tetanus and pertussis combined vaccine) at 2 months, 4 months, 6 months and 18 months after birth, and 4 to 5 years of age. In 1990, the World Health Organization said that 80% of children had been vaccinated against illness. Small variola is a big problem for the two fighters and ultimately brings benefits to settlers. Little pox spread through British and American troops, but Americans have developed a vaccination method - vaccine. They plunged to healthy people to take a little pox from the patient and to help their bodies learn to fight it as soon as possible so that their bodies can later fight the virus. Because of small pox, Britain could not find this way and soon lost soldiers. Their earlier advantage was British as they were shipping soldiers on board. Small variolas are truly deadly, but humans have weapons, ie vaccinia. In the late 1700's, Dr. Jenner noticed that dairy maid with mild vaccinia had never infected small pox. On May 14, 1776, he infected the boy named James Phpps with vaccinia and caused a small pustule. Then Dr. Jenner infected the boy with small pox, but he did not suffer small pox. Dr. Jenner found the only defense against small pox. This vaccine is very effective as there is no other smallpox host. This is the only owner who is a wise man. As a result, the World Health Organization launched a global plan to eradicate small variola, and they began vaccinating dozens of people. I am occurring, they go there to isolate people infected with smallpox, and vaccinate people around the area where the infected person was found. On December 9, 1979, Bangladesh reported the last case of small smallpox and therefore eradicated smallpox.

Edward Anthony Jenner, also known as "father of immunology", is a British scientist known for the discovery of smallpox vaccine. This is the first successful vaccine developed so far and continues to be the only effective prophylactic treatment for fatal smallpox. His discovery was a major medical advance to save countless lives. In 1980, the World Health Organization announced that smallpox is a disease of eradication. In 1770, after completing 7 years of training as a surgeon in Gloucestershire State, I went to St. George's Hospital under the guidance of prominent surgeon John Hunt. Study anatomy and surgery. After finishing his research, he returned to Berkeley to establish medical practice until his death. Jenner and his colleagues read the paper on medical science in Gloucestershire State Rodderboro and founded the medical community to eat together. He also published useful papers on angina pectoris Jenner works in rural society. Most of his patients are farmers or work on cattle farms. In the 18th century, smallpox was considered the most deadly and most persistent human pathogenic disease. Prophylaxis of smallpox by immunization brought success to the Dutch physiologist Jan Ingenhaus and was brought to the UK by Mary Wortly Montague, Mrs. British Ambassador to Turkey in 1721 in the UK. This method is well known in eastern countries and involves scratching the veins of a healthy person and pushing a small amount of material (from a small pustule of a mildly attacked person) into the wound. The risk of treatment is that patients often infect complete diseases and lead to fatal consequences. In 1788, the wave of smallpox infiltrated Gloucestershire State, treated with cattle in outbreaks, patients infected with lighter disease vaccinia have never been infected with smallpox Absent. Jenner needs a way to prove that his theory is really effective. In 1796, Jenner conducted an experiment with one of his young patients, James Phipps, an eight-year old boy. After cutting James' arms twice, Jenner made a small amount of vaccinia for them. The boy showed normal reaction and showed a mild fever, but it got better soon after a few days. Several weeks later, Jenner repeated vaccinations and used the material of smallpox to keep the boy healthy. This is the way Jenner makes vaccinations, named after the medical names of vaccinia and vaccinia. In 1798, after a more successful test, he published his findings: Variolae Vaccinae, an investigation of the causes and effects of illness known as the name of vaccinia. Jenner was found to have a stroke in January 1823. He never recovered completely, and on January 26, 1823 he died of a 73-year-old stroke in Berkeley, Gloucestershire, England. In England, in the late 1790s, physician Edward Jenner discovered how to vaccinate people with smallpox vaccine. About 190 years later in 1980, it was declared that smallpox was eradicated (Edward Jenner). Today, humans continue to trace Jenner's footprints and continue working to treat and eradicate diseases threatening people all over the world. - Although vaccination has been in place for a long time, the controversy over these uses has declined significantly when the vaccine was first received. Over time, vaccines have been developed for diseases such as polio, varicella, varicella, and general influenza, as well as improvements and constant innovation. Prior to the development of the vaccine disease had become a big problem as it spread rapidly over a wide range. According to Harvard Medical School data, British rural doctor Edward Jenner produced the first vaccine in 1796. Jenner developed a small pox vaccine that changed the course of this deadly disease. Since then, many other researchers and doctors have developed other vaccines. When the vaccine reaches your child's health, the vaccine has both advantages and disadvantages, and some parents are working hard to make vaccination decisions. Using a vaccine can prevent you

William Butler Yeats: Modernist William Butler Yeats is an Irish poet of the 19th century. William Butler Yeats was born in Dublin, Ireland in 1865. He was educated in Dublin and London and in 1877 wrote his first passage (nobelprize.org). He wrote many poems in his life and was considered to be the most influential poet of his time. He is very influential in the modernist era. William Butler Yeats is one of the most famous poets of the 19th century. - The paragraphs described are on pages 222 - 266 of M. T. "Life without a surprising Octavian". Anderson It explains the scientific papers by Gitney and Sharpe and the letter from Dr. Trefusis, a document about the death of Cassiopeia, a memoir written by Octavia (a poem written by Theoginis). These pages start with Smallpox disease of Smallpox, Octavian 29-year-old mother, Cassiopeia William Butler Yeats was born in Dublin, Ireland on 13th June 1865. He is the oldest of the four children of portrait painter John Butler Yeats. His father took part in William's regular school education at home. John Yeats has a strong personality. His personal philosophy incorporates aesthetics (belief that art and beauty are important to all) and atheism (a belief that God does not exist). William felt its effect was slow as it appeared in his interest in magic and occultism (supernatural).

Theresa Knorr is the mother of six children sentenced to murder the two daughters, Suesan Knorr (16) and Sheila Sanders (20). Theresa has abused all her children for many years, but she has deeper hatred for her girls and causes them to die. The surviving daughter, Trick Norle, finally convicted her mother by killing her sister. Terry and her brothers and sisters experienced years of torture, physical and sexual behavior before their mothers were arrested. Terry explained that her brother and her mother abused them severely. Maria Theresia married Francis I of Lorraine. Maria Theresa is one of the few people marrying a lover. She likes her husband very much. She has sixteen children, eleven daughters (of which 10 are "Maria") and five sons. Her youngest daughter, Maria Antonia, is known for her French name Marie Antoinette who marries Louis XVI of France later in France. After her husband's death, Maria Theresia made his son Joseph II a joint regulator of the Austrian ruler, but in reality she leaves most of her power to herself, which leads to her and her son It was. Joseph was able to fully demonstrate his ability until she was tense. In April 1770, Maria Theresa's youngest daughter, Maria Antonia, represented the Viennese Louis and the French doves. Maria Anthony's education was ignored and her mother taught Versailles and French as much as possible when the French showed interest in her. Maria Theresa and Maria Antonia (now known as Marie Antoinette) maintain biweekly communication and she contemptly reprimands that she is not pregnant often despising that she reprimanded her. After the birthday of her 50th birthday in May 1767, Maria Theresia signed her daughter-in-law, Maria Josefa, Bavaria and smallpox. She survived, but the new queen did not survive. Then Maria Theresia forced her to join her in the Queen's cellar to pray next to the sealed Maria Joseph sealed by the daughter of Archbishop Maria Josepha. Daimo started appearing with a smallpox rash two days after visiting the basement and died soon. Maria Carolina appoints her to Bride of Feldinand IV of Naples IV. Maria Theresa condemned her life due to the rest of her daughter and it is believed that Maria Joseph captured the smallpox from the late of the late Queen as the concept of prolonging the incubation period was scarcely known It was.

Known as the founder of Immunology Edward Anthony Jenner has laid the foundation for modern vaccines by paving the way for eliminating previously unavoidable diseases such as smallpox (information source). The results of his work can be seen in modern healthcare. Edward made a great contribution to this study and saved a lot of lives in his invention of the smallpox vaccine. Edward Jenner was born on May 17, 1749 in Berkeley, Gloucestershire State. He is the eighth child of nine children. His father was a pastor in Berkeley and he began receiving education since he was very young. Edward Jenner and the vaccine found that Edward Jenner (1749-1823) was trained in London under the training of John Hunt and was a military surgeon. After that he spent all his career in his homeland in Gloucestershire (West of England). His research is based on a careful case study and clinical observations over 100 years before scientists can explain real viruses and diseases. His innovative approach is successful ... Impact of tuberculosis vaccine Summary Tuberculosis is one of the most infectious diseases in the world. Since nearly one-third of the world's people are infected with this virus, efforts are being made to prevent the spread of this disease (NIAID, 2001). One method for preventing tuberculosis is the BCG (Balmette and Guerin Bacillus) vaccine. In the beginning of the 20th century, Calmet and Guerin worked together to isolate the diseased strains, and made the first BCG vaccine. Whole century In the UK, in the late 1790s, physician Edward Jenner discovered how to vaccinate people with smallpox vaccine. About 190 years later in 1980, it was declared that smallpox was eradicated (Edward Jenner). Today, humans keep track of Jenner's footprints and continue working to treat and eradicate diseases threatening people around the world. - Although vaccination has been in place for a long time, the controversy over these uses has declined significantly when the vaccine was first received. Over time, vaccines have been developed for diseases such as polio, varicella, varicella, and general influenza, as well as improvements and constant innovation. Prior to the development of the vaccine, the disease was widely and rapidly spreading, so it became of great concern. Like other doctors at the time, Edward Jenner made changes to protect his patient from smallpox. However, from the beginning of his career, Edward Jenner was fascinated by a national legend that said those who caught vaccinia from cattle could not catch smallpox. This and the experience as a mutation of his own boy and its associated risk made him the most important study of his life. Vaccinia is a mild bovine virus infection. It creates some crying spots on the chest, but it has little sense of incongruity. Milk maid women may catch vaccinia from cattle. They feel that colors are quite a few days, and usually feel a small amount of acne scars in their hands, but this disease is not a problem for them.

Indian Infections and Deaths in the New World The conquest of the New World by Europeans is caused not by guns, swords or barbarous acts but by invisible and dangerous bacteria. Infectious diseases have played an important role in shaping the conquest of the new world. Many of the territory of America died of various diseases. For centuries after Columbus landed in the New World on October 12, 1492, more indigenous Americans die each year due to infections caused by European colonists, not by nature It is often said (Meltzer 38). Most of the conquests took place without battle or war as the first contact of the Europeans in the New World led to illness. Old world infectious diseases left devastating signs in the Indian culture of the new world. In particular, smallpox spread rapidly in Panama, destroying the entire population. Once the disease enters the Andes, its south spread will result in the most devastating loss of life in the Americas. People of the New World including Incas lose immunity and decrease by two thirds Older world invaders brought about many infectious diseases. There is no new world at all, but there are no old world figures. Smallpox is a standard infectious disease in Europe and most of the old world in 1491. It occupied the location of the New World region at the beginning of the next century and killed many American Indians from Aztecs and Mexicans. And Peru. People want to know how hundreds of Spaniards conquered these huge Indian Empires. Look back at the record You will find the army Generally, the people of the Indian Empire are destroyed by diseases like smallpox, malaria, and various infectious diseases. I do not seem to be as much as India's illness. "The exchange of infectious diseases between the old world and its American and Australian colonies is a wonderful one-sided one," Alfred Crosby writes in ecological imperialism, another wonderful book. "Sexually transmitted infection syphilis may be the only important export of diseases in the new world ..." The cause of this epidemiological poverty is speculation. Of course, as I mentioned in this article, the relative lack of livestock saves the Indians from so-called zoonotic infections. But, no one can be sure of it

In the centuries after Columbus landed in the New World on October 12, 1492, it is often said that many indigenous people died annually due to infections caused by European settlers. I was not born. "(6) Destruction of indigenous peoples by diseases caused by European invaders is unprecedented. It is difficult to accurately determine Colombian former American population, but scholars estimate that this number is between 40 and 50 million. Older world invaders brought about many infectious diseases. There is no new world at all, but there are no old world figures. Smallpox is a standard infectious disease in Europe and most of the old world in 1491. It occupied the location of the New World region at the beginning of the next century and killed many American Indians from Aztecs and Mexicans. And Peru. People want to know how hundreds of Spaniards conquered these huge Indian Empires. Look back at the record You will find the army Generally, the people of the Indian Empire are destroyed by diseases like smallpox, malaria, and various infectious diseases. Most of the conquests took place without battle or war as the first contact of the Europeans in the New World led to illness. Old world infectious diseases left devastating signs in the Indian culture of the new world. In particular, smallpox spread rapidly in Panama, destroying the entire population. Once the disease enters the Andes, its south spread will result in the most devastating loss of life in the Americas. People of the New World including Incas lose immunity and decrease by two thirds • When Europeans came to the New World, they brought many diseases that destroy Native Americans. These diseases include: smallpox, influenza, typhus, measles, malaria, whooping cough. Currently, the Native American dies and European settlers need a new form of labor, they turn to Africa and use African-American slaves as free labor. · The exchange of Colombia is a movement between people, culture, thoughts and diseases between the New World and the Old World. These items are exchanged through exploration and Atlantic slave trade. Items from the old world include livestock (cattle, sheep, pigs, horses), cereals (wheat, rice, barley, oats), peaches, pears, coffee beans, radish, olives, onions, diseases. Items from the New World include pepper, pumpkin, tobacco, turkey, peanut, pineapple, potato, cocoa, tomato, beans, corn, herbs and so on.

Little poxÄ) Who was introduced to Europe by Mary Montagu B) Where; China and India C) When the 4 th century China, 7 th century India II. History of the disease: (Including recent research and development and development of therapy, due to the fear of biological warfare America and Russia will not destroy small smallpox culture.In arguing human achievement , Arrogance III. Reason: Normally spread between two people by droplets of nose and mouth replicated from lymphatic tissue. For the two fighters, small variolas are a big problem and ultimately bring benefits to settlers. Little pox spread through British and American troops, but Americans have developed a vaccination method - vaccine. They plunged to healthy people to take a little pox from the patient and to help their bodies learn to fight it as soon as possible so that their bodies can later fight the virus. Because of small pox, Britain could not find this way and soon lost the soldier. Their earlier advantage was British as they were shipping soldiers on board. Small variolas are truly deadly, but humans have weapons, ie vaccinia. In the late 1700's, Dr. Jenner noticed that dairy maid with mild vaccinia had never infected small pox. On May 14, 1776, he infected the boy named James Phpps with vaccinia and caused a small pustule. Then Dr. Jenner infected the boy with small pox, but he did not suffer small pox. Dr. Jenner found the only defense against small pox. This vaccine is very effective as there is no other smallpox host. This is the only owner who is a wise man. As a result, the World Health Organization launched a global plan to eradicate small variola, and they began vaccinating dozens of people. I am occurring, they go there to isolate people infected with smallpox, and vaccinate people around the area where the infected person was found. On December 9, 1979, Bangladesh reported the last case of small smallpox and therefore eradicated smallpox. Small Pox & lt; Tab / & gt; Smallpox Virus & lt; Tab / & gt; Small Pox Vaccine is not manufactured or registered for use in Australia. Over 20 years ago commercial production of small pox vaccines in the world ceased. Edward Jenner found the first vaccine, the small pox vaccine so far. This vaccination resulted in effective protection of the disease by stimulating the production of antibodies against diphtheria toxin, a toxigenic strain of acne diphtheria, clostridium difficile. In Australia, the diphtheria vaccine exists in the form of DTP (diphtheria, tetanus and pertussis combined vaccine) at 2 months, 4 months, 6 months and 18 months after birth, and 4 to 5 years of age. In 1990, the World Health Organization said that 80% of children had been vaccinated against illness.

The devil in the refrigerator of Richard Preston is an interesting book that discusses the anthrax terrorist attack after 9/11 attack and the fact that smallpox is a threat to the world from future bioterrorism. This book provides a brief history of smallpox, including epidemic details in 1970 in Germany. This disease was eradicated in 1979 by the World Health Organization's aggressive vaccine program. After the virus no longer treats, the World Health Organization ceased recommending smallpox vaccination. When Richard Preston started writing a devil in the fridge, I think he was going to talk about that smallpox to that book - it eliminates it based on accident, war or terrorism and revives it potentially It is. However, after anthrax shipment carried out shortly after 9/11 attack, the authors felt the need to incorporate anthrax investigation into his ongoing work. This is just a theory, but you can explain the split personality of the book. The bibliography of this book version only mentioned the struggle against smallpox, but the explanation started with the first anthrax attack and then backed back to the smallpox eradication program 20 years ago. The eradication of smallpox and the history of subsequent discussion and research occupies the rest of the book until the end of the two disease / biological weapons associations. Richard Preston 's book "The Devil in the Refrigerator" is about the eradication of smallpox and anthrax panic since 9/11. This book starts with an old man with anthrax. Later, a letter wrapping high quality anthrax was sent to the office building of the Heart Senate. Then, in 1978 the theme of the book suddenly changed to eradicate smallpox. The last line of smallpox before failure was Bangladesh, but the last case was UK in 1979. After eradicating smallpox there was a threat of many bioterrorism, and when another letter was sent to the senator, the book goes back to anthrax. The quality of B. anthracis was very high, as it passed through the hole in the envelope, three mailman also died of B. anthracis. I could not find anyone who sent the letter, but I suspect that I have a letter from al-Qaeda or Caucasian male. Most information on this is still classified, so there is no name. Fortunately, the "devil in the fridge" provides me with a timely opportunity to understand bioterrorism and related concepts - biological warfare, weapons of mass destruction - and so on. This is clearly an urgent task against human burden. In the not too distant future, the threat of nuclear destruction and destruction. But this is the only bioterror problem I have ever had, especially smallpox and anthrax.

Vaccines are a modern type of medicine added to the world early in life. It is mainly called modern medicine because it has saved lives all over the world. Vaccines dates back to ancient Greece and is thought to have occurred in ancient Greece. There are many different vaccines and their causes. The term vaccine is in Latin, from the "vacca" of cattle, and patients with vaccinia are currently not immunized with smallpox. Edward Jenner was a British doctor in Berkeley, England, and began vaccinating. Despite the dangerous side effects, the vaccine history began with the vaccination of smallpox developed by Edward Jenner, as more sites need to be vaccinated, and ended in extreme discussion It was. There are essential vaccine measures in 42 states, and many children have to receive at least 22 vaccinations before first grade. Immunization is a controversial topic among health care professionals because of possible health risks. Despite the general idea, I actually received immunization Vaccines since the 11th century See the timeline of the preventable disease detection and the history of epidemic diseases and vaccine development; participate in activities to learn how to make and work vaccines; and Philadelphia doctor parents and / or medical professionals A vaccine history website developed by the university that gains access to immune resources for the home Human beings have benefited from the vaccine for more than two centuries. But the path to an effective vaccine is neither a neat nor a direct one. In this article I will explore the history of vaccination and vaccination First, Edward Jenner made the world's first smallpox vaccine in the 1790s. He also proved many of the problems of the Jenner era, including the need for a secure funding mechanism, simplification of manufacturing and safety issues, and general deep concern over immunization. We propose that historical perception helps to provide a viable long term solution to the contemporary problems in vaccine research, manufacture and supply.

It is difficult to imagine a world without a vaccine - the "disease" of the world has potentially deadly (body or at least irreparable damage of the cause). In this world, the disease has killed millions of bright child eyes. Fortunately, with the development of vaccines, the population has grown bigger and healthier in the past century. Sadly, despite improvements in our lives, many have not decided yet - or strongly disagree - children will be immunized. They claim that vaccination is dangerous and causes autism and other diseases. Today's medications are offered in several ways, including the use of needle and syringe vaccination. If the needle pain suddenly disappears, what will you think? Over the past several hundred years, medical advances have made wonderful progress, and we became a patient not to accept the point of injectable form of the liquid of the vaccine. According to Mark Kendall, an Australian scientist or biomedical engineer says it is stupid, his new invention Nanopatch has become an effective way of vaccination, which is cheaper than needle and syringe Is, the cold chain is more likely to be deleted It has the ability to improve immunogenicity In 1961, the bifurcated needle was developed as a more efficient and cost-effective alternative, and the main instruments used during exercise were eradicated from 1966 to 1977. Bifurcated needle vaccination requires only the quarter of the traditional method needed to carry out a simple amount of vaccine. Upon success in the production of the intensification eradication program used for smallpox vaccine, eradication of smallpox vaccine after the success by modern cell culture techniques to produce the end or the opposite of the stage known as the first generation vaccine Has been developed. Production of the same generation of smallpox and first generation vaccine or cloned virus as the same smallpox vaccine strain mutant The third generation smallpox vaccine purified from a conventional vaccine strain was used for eradication at the end of the stage It represents a more safe vaccine specially developed Further through cultivation and animal attenuated vaccine strains Currently, the official smallpox vaccine is a live virus prepared infectious vaccinia virus. Solution using bifurcated immersion vaccine (Nisata) vaccine needle management. A needle to puncture the skin (usually the upper arm) multiple times within a few seconds. If successful, a vaccine site or itching red clump will be displayed in 3 to 4 days. In the first week, the bump will be filled with pus (called "Jenner vesicles") big blister, will start the drain. In the second week, the blisters dried and started to scab. We will leave a small scar in the third week of the scab and fall

Mr. Mary Wortli Montagu's Lovers: Love Song Literature is an art form and has many aspects but some are obvious and some are subtle. The surface of literature consists of various elements such as genre, shape, rhythm, tune, vocabulary, sentence structure. Depending on the period, personal style of the writer, and the type of work, the elements used in literature are determined. A more subtle aspect of literature is the use of the meanings of symbols, images, and works. In most literary works you can create similarities between writers' personalities and current life events by using themes, characters, and specific literary techniques. After witnessing the incident during her trip to the Ottoman Empire, Mary Waltree Montague despised Western tradition by smallpox vaccination to Western medicine. In 1718, Waitley Montague was vaccinated by her son and her daughter was vaccinated when she was attacked in England in 1721. This is the first such action in the UK. She persuaded Carolyn of Ansbach to try prisoners treatment. Princess Caroline later vaccinated the two daughters in 1722. According to the pen name, Wortley Montague explained vaccination in September 1722 and announced a supporting article. It is a continuing support of British aristocratic Mary Waltree Montague (Figure 22), responsible for introducing British variability (10). In 1715, Mrs. Montague suffered a smallpox accident, seriously damaging her beauty. For 18 months, Mrs. Montague's husband, Edward Wartree Montagu, was appointed ambassador for sublimation. A few weeks after they arrived in Istanbul, Mrs. Montague wrote to her. A friend about the variation method used in the Ottoman court. Mrs. Montague decided to prevent Smallpox from hitting her and ordered the embassy surgeon Charles Maitland to vaccinate her five - year - old son. After the vaccination program returned to London in April 1718 in March, Mrs. Montague asked Charles Maitland to vaccinate a 4 year old daughter in front of a Royal Court doctor.

In the 7 to 2 ruling, the prime minister decided that the safety and health of Massachusetts citizens were better than individual rights, and Massachusetts and the US constitutional mandatory immunization were constitutional. Withdrawn from this decision for more than 100 years, this case is still discussed and analyzed in academic writing and shows the continued tension and conflict relevance. The US Supreme Court quoted this case 69 times before 2004 (5). The facts of Jacobson vs. Massachusetts fully explain the economic analysis of immunization, the first Constitutional Supreme Court action against mandatory immunization laws. The case involved the Massachusetts law which allowed municipalities to vaccinate smallpox vaccines for public health and safety regulations as needed. After that, after judging that smallpox was "spreading somehow" and "continued to increase", the city of Cambridge passed the mandatory immunization regulation. This order is an economic way that the benefits of mandatory vaccination outweigh the costs of providing vaccines, discovering and investigating resistance (Jacobson etc.), and allowing individuals to decide whether to vaccinate It represents a decision. This forced vaccination program eventually led to the famous Jacobson v. Massachusetts incident. The case was the result of the refusal of immunization by Cambridge residents. The Swedish immigrant Henning Jacobson refused to get vaccinated for fear of his being sick. He insisted that the previous smallpox vaccine became sick when he was a child. Instead of paying a $ 5 fine, he challenged the state's forces to force vaccinations on people. His lawsuit failed at the state level, but Jacobson appealed the ruling, so this case was heard in the Supreme Court. In 1905, the Supreme Court upheld the law of Massachusetts: reportedly Jacobson could not refuse mandatory immunization First of all, the US Supreme Court has never directly decided to grant religious immunization against forced vaccination, but the court established the right to receive state vaccinations as Jacobson v. Massachusetts stated. This decision has been strongly advocated by frequently exempted opponents, which clearly shows the broader powers of the state in this area. McCarthy v. Bozeman, 212 F. According to 2d 945 (2002), the District Court judge dismissed the State of Arkansas State and requested religious exempt applicants to belong to an accredited religious organization for vaccination, the procedure for obtaining immunity is 1 and 14 th corrections were violated.

Edward Jenner and the vaccine found that Edward Jenner (1749-1823) was trained in London under the training of John Hunt and was a military surgeon. After that he spent all his career in his homeland in Gloucestershire (West of England). His research is based on a careful case study and clinical observations over 100 years before scientists can explain real viruses and diseases. His innovative approach succeeded and by 1840 the British government banned alternative prophylaxis of smallpox. Edward Jenner and the vaccine found that Edward Jenner (1749-1823) was trained in London under the training of John Hunt and was a military surgeon. After that he spent all his career in his homeland in Gloucestershire (West of England). His research is based on a careful case study and clinical observations over 100 years before scientists can explain real viruses and diseases. His innovative approach is successful ... Impact of tuberculosis vaccine Summary Tuberculosis is one of the most infectious diseases in the world. Since nearly one-third of the world's people are infected with this virus, efforts are being made to prevent the spread of this disease (NIAID, 2001). One method for preventing tuberculosis is the BCG (Balmette and Guerin Bacillus) vaccine. In the beginning of the 20th century, Calmet and Guerin worked together to isolate the diseased strains, and made the first BCG vaccine. Whole century Edward Anthony Jenner, also known as "father of immunology", is a British scientist known for the discovery of smallpox vaccine. This is the first successful vaccine developed so far and continues to be the only effective prophylactic treatment for fatal smallpox. His discovery was a big medical advance that saved countless lives. In 1980, the World Health Organization announced that smallpox is a disease of eradication. After completing the seven-year training as a surgeon in Gloucestershire in 1770, I went to St. George's Hospital under the guidance of prominent surgeon John Hunt. Study anatomy and surgery. After finishing his study, he returned to Berkeley to establish medical practice until his death.

Edward Jenner "Now James, I need to try that you are completely stationary.It may hurt your arms when I cut, please extend my arms Do not move my arms "I am at the office, his name is Edward Jenner, and I am the last sentence before he finished the first test, I am in the office, Is one of the themes I found for treatment. Edward Jenner and the vaccine found that Edward Jenner (1749-1823) was trained in London under the training of John Hunt and was a military surgeon. After that he spent all his career in his homeland in Gloucestershire (West of England). His research is based on a careful case study and clinical observations over 100 years before scientists can explain real viruses and diseases. His innovative approach is successful ... Impact of tuberculosis vaccine Summary Tuberculosis is one of the most infectious diseases in the world. Since nearly one-third of the world's people are infected with this virus, efforts are being made to prevent the spread of this disease (NIAID, 2001). One method for preventing tuberculosis is the BCG (Balmette and Guerin Bacillus) vaccine. In the beginning of the 20th century, Calmet and Guerin worked together to isolate the diseased strains, and made the first BCG vaccine. Whole century In the UK, in the late 1790s, physician Edward Jenner discovered how to vaccinate people with smallpox vaccine. About 190 years later in 1980, it was declared that smallpox was eradicated (Edward Jenner). Today, humans keep track of Jenner's footprints and continue working to treat and eradicate diseases threatening people around the world. - Although vaccination has been in place for a long time, the controversy over these uses has declined significantly when the vaccine was first received. Over time, vaccines have been developed for diseases such as polio, varicella, varicella, and general influenza, as well as improvements and constant innovation. Prior to the development of the vaccine, the disease was widely and rapidly spreading, so it became of great concern. Like other doctors at the time, Edward Jenner made changes to protect his patient from smallpox. However, from the beginning of his career, Edward Jenner was fascinated by a national legend that said those who caught vaccinia from cattle could not catch smallpox. This and the experience as a mutation of his own boy and its associated risk made him the most important study of his life. Vaccinia is a mild bovine virus infection. It creates some crying spots on the chest, but it has little sense of incongruity. Milk maid women may catch vaccinia from cattle. They feel that colors are quite a few days, and usually feel a small amount of acne scars in their hands, but this disease is not a problem for them.

Small pox and small pox were the most feared diseases that were once known to man, and began in the era of Christopher Columbus. The aim of this disease is to change the lives of people in worse ways. It is called epidemic disease, eventually killing hundreds of people. Small small pox originated in Hispaniola, and it could not be cured, so it went to Puerto Rico and then to Cuba. It is a matter of time before it spreads to the mainland somewhere in the United States. In the Middle Ages, small variola is a highly contagious disease and often leads to death if left untreated. For the two fighters, small variolas are a big problem and ultimately bring benefits to settlers. Little pox spread through British and American troops, but Americans have developed a vaccination method - vaccine. They plunged to healthy people to take a little pox from the patient and to help their bodies learn to fight it as soon as possible so that their bodies can later fight the virus. Because of small pox, Britain could not find this way and soon lost the soldier. Their earlier advantage was British as they were shipping soldiers on board. Small variolas are truly deadly, but humans have weapons, ie vaccinia. In the late 1700's, Dr. Jenner noticed that dairy maid with mild vaccinia had never infected small pox. On May 14, 1776, he infected the boy named James Phpps with vaccinia and caused a small pustule. Then Dr. Jenner infected the boy with small pox, but he did not suffer small pox. Dr. Jenner found the only defense against small pox. This vaccine is very effective as there is no other smallpox host. This is the only owner who is a wise man. As a result, the World Health Organization launched a global plan to eradicate small variola, and they began vaccinating dozens of people. I am occurring, they go there to isolate people infected with smallpox, and vaccinate people around the area where the infected person was found. On December 9, 1979, Bangladesh reported the last case of small smallpox and therefore eradicated smallpox. Small Pox & lt; Tab / & gt; Smallpox Virus & lt; Tab / & gt; Small Pox Vaccine is not manufactured or registered for use in Australia. Over 20 years ago commercial production of small pox vaccines in the world ceased. Edward Jenner found the first vaccine, the small pox vaccine so far. This vaccination resulted in effective protection of the disease by stimulating the production of antibodies against diphtheria toxin, a toxigenic strain of acne diphtheria, clostridium difficile. In Australia, the diphtheria vaccine exists in the form of DTP (diphtheria, tetanus and pertussis combined vaccine) at 2 months, 4 months, 6 months and 18 months after birth, and 4 to 5 years of age. In 1990, the World Health Organization said that 80% of children had been vaccinated against illness.

"They believe that I am trapped in the machine, it is impossible to open it, this is the design they gave to my husband." Here, once again, another culture I acknowledge that it is different from her own culture. Judith is still aware of her way of doing. "Focuses not to get caught up in the cliché of Orientalism of the early modern male travel books, the identity of her personality and behavior proved her writing from the beginning to the last letter. Lady Mary Wortley Montagu (1689-1762), a British aristocrat and author, remembers letters from Turkey today. This is an early example of secular work in eastern Islam by women in the West. When Mary entered the Ottoman Empire, she discovered local variations of habit, inoculation of smallpox. Unlike Jenner later using a vaccinia vaccine, the variation uses a small portion of the smallpox itself. Mary, who is suffering from this disease, encourages her children to vaccinate in Turkey. After she returned to London, she diligently promoted surgery but encountered many resistance. But her example certainly promotes the practice of injecting smallpox in the UK upper class. The number of vaccinations is still small, and the whole medical activity in the 18th century focused on reducing the risks and side effects of the vaccination process. After witnessing the incident during her trip to the Ottoman Empire, Mary Waltree Montague despised Western tradition by smallpox vaccination to Western medicine. In 1718, Waitley Montague was vaccinated by her son and her daughter was vaccinated when she was attacked in England in 1721. This is the first such action in the UK. She persuaded Carolyn of Ansbach to try prisoners treatment. Princess Caroline later vaccinated the two daughters in 1722. According to the pen name, Wortley Montague explained vaccination in September 1722 and announced a supporting article.

Edward Jenner, born in England in the mid 18th century, will eventually become one of the most famous scientists in medical history and become so-called "father of immunology." After observing that vaccinia infection can protect people from smallpox, Jenner was vaccinated with an 8 - year - old boy with varicella in the hands of British milk maid. Then he repeatedly tried to "challenge" immunization by exposing the boy to the material of smallpox - but that boy never got sick. Jenner proved its smallpox immunity Jenner's smallpox vaccination method became increasingly common and ultimately replaced the mutation that was the standard before his demonstration. About 150 years after Jenny died in 1823, smallpox will be the last gasping in the second half of the 20th century. After extensive monitoring and vaccination programs, it will eventually be eliminated - thanks to the initial efforts of the immunologist's father mostly thanks Edward Jenner's later years. Edward Jenner Museum. It is available from http://www.jennermuseum.com/Jenner/edwardjenner% 27sla.html. In short, Edward Jenner was one of the greatest discoveries in history, but his method and his data were flawed. Then his study was dismissed until vaccination was performed. Finally, Edward Jenner discovered that vaccinia can prevent smallpox, despite his lack of data and inaccuracy. When Edward Jenner introduced vaccination in 1796, there was a long history of immunization, a more primitive form of vaccination, including the introduction of deliberate diseases into the body. Like in Voltaire in the 18th century, the philosopher regretted his French attitude towards smallpox vaccination: in 1876, after a group of local representatives were elected anti-vaccination platform, they were riot I refused to enforce. Forced vaccines According to the London Times, these streets are "threatened because they are surrounded by a group of densely popular mobs, and the intention to rescue the prisoners is revealed soon". Despite the dangerous side effects, the vaccine history began with the vaccination of smallpox developed by Edward Jenner, as it is necessary to vaccinate more sites. 42 states have an essential vaccine policy, and many children must be vaccinated with at least 22 vaccines before first grade. Vaccination is a topic controversial among medical professionals as there is a possibility of health risk. Immunization is actually Immunization is designed to help people survive their daily lives. Eddie Jenner, a rural doctor who lived in Berkeley, England, began immunization in 1796 (Ministry of Health and Welfare). Throughout history, vaccinations are getting better for safer people. To maintain good health, everyone should receive vaccinations against certain diseases. Vaccines have been shown to immunize people to heavy sickness (child immunity). - Every year, thousands of Americans die of seasonal influenza. With this amazing statistic, the U.S. government strongly urged domestic and its children to vaccinate during the upcoming influenza season in November.

Smallpox is always one of the most dangerous and deadly curse in human history. Even such diseases as plague, cholera and yellow fever do not have such widespread impact. Smallpox is a parasitic virus (virus harmful to the host) called Balihora virus. It can only be transmitted through the population and is considered "crowd disease" which requires densely populated areas to survive. It disappears when the virus is blocked from the new host. Smallpox spread through the so-called "droplet infection". "Water droplets" are body fluids that escape to the outside air such as moisture when sneezing. Smallpox 1518-1977: "Smallpox disease is at least 3,000 years old, confirmed in China and India" (Brock 122). In the 17th and 18th centuries, small smallpox was the most serious infection in the west. Europeans have developed a genetic trait that makes them immune to small pox. When they traveled to the USA, they resulted in small pox, and the disease ran out of the population: symptoms include sudden fever, headache, back pain, vomiting and convulsions. A clear rash appears after about 2 to 3 days after symptoms appear, and smallpox is diagnosed. The rash begins with small pink spots and then turns to blisters. After all, they left hard and depressed wounds in the deep part of the skin. The hard material left behind contains variola virus. Death usually occurs between 11th and 15th (Brock 132) Small variola is a big problem for the two fighters and ultimately brings benefits to settlers. Little pox spread through British and American troops, but Americans have developed a vaccination method - vaccine. They plunged to healthy people to take a little pox from the patient and to help their bodies learn to fight it as soon as possible so that their bodies can later fight the virus. Because of small pox, Britain could not find this way and soon lost soldiers. Their earlier advantage was British as they were shipping soldiers on board. Small variolas are truly deadly, but humans have weapons, ie vaccinia. In the late 1700's, Dr. Jenner noticed that dairy maid with mild vaccinia had never infected small pox. On May 14, 1776, he infected the boy named James Phpps with vaccinia and caused a small pustule. Then Dr. Jenner infected the boy with small pox, but he did not suffer small pox. Dr. Jenner found the only defense against small pox. This vaccine is very effective as there is no other smallpox host. This is the only owner who is a wise man. As a result, the World Health Organization launched a global plan to eradicate small variola, and they began vaccinating dozens of people. I am occurring, they go there to isolate people infected with smallpox, and vaccinate people around the area where the infected person was found. On December 9, 1979, Bangladesh reported the last case of small smallpox and therefore eradicated smallpox.

Immunization Vaccination history does not start with the first vaccination itself, it is an infectious disease that greatly affects the population. In 1796, Edward Jenner used vaccinia to create effective immune components in the continued growth of smallpox. Jenner's approach finally underwent medical and technical changes over 200 years, up to the complete elimination of smallpox. Vaccination has been a controversial medical topic for many years and it has been proved to be an effective means to prevent serious consequences including mortality from childhood illness, but there still remains controversy . The history of the vaccine includes obvious risks and injuries. But over and over again, doctors, scientists and governments have changed the vaccine and vaccine policy to make the vaccine safer. Sometimes changes are made to eliminate concerns that are relatively unfounded but widely felt, such as removing thiomersal from the vaccine. Nevertheless, supporters of vaccines should continue to appreciate the need for ongoing research to identify and mitigate the slight dangers posed by vaccines and even minor risks. Immunization Vaccination history does not start with the first vaccination itself, it is an infectious disease that greatly affects the population. In 1796, Edward Jenner used vaccinia to create effective immune components in the continued growth of smallpox. Jenner's approach finally underwent medical and technical changes over 200 years, up to the complete elimination of smallpox. Vaccination has been a controversial medical topic for many years and it has been proved to be an effective means to prevent serious consequences including mortality from childhood illness, but there still remains controversy . Historical evidence has a predictable and inverse relationship between the level of disease that can be prevented by the vaccine and safety issues and safety issues can arise as the direct experience of the vaccine preventable disease decreases It suggests that there is sex. Today, vaccines are one of the most important medical advances in history, and are useful for the prevention of numerous vaccine preventable diseases, as well as countless human sufferings and disorders. Due to the discovery of vaccines in the 20th century, the parents of the 21st century and many health care providers have limited or no effect on diseases such as polio, smallpox, measles. This brought an uneasy relationship between the public and public health managers. In a recent survey of pediatricians and family physicians, 11% of physicians did not encourage parents to vaccinate children with all available vaccines.

Edward Jenner is a British countryside doctor who introduced the smallpox vaccine. Jenner is an avid practitioner of smallpox vaccination and has pushed this principle step by inducing immunity against this fatal disease by exposure to harmless related diseases. His technique provides more secure and reliable protection than traditional immunization. Working in rural areas, Jenner knows that milk maid had never had small village folk customs. They are known for their relatively perfect skin tone, it does not have small scratches. However, they inevitably caught vaccinia through close cooperation with cattle. Jenner estimated that the wave of vaccinia produced immune to smallpox and even encountered local people who deliberately infected themselves to cause this reaction. As a positive doctor who likes experimentation, Jenner wants to prove his theory. In 1796 he inserted the pus of a female Salanel female to milk with Vaccinia on the cut of the arms of a local boys James Phipps. A few days later, Jenner exposed the boy to smallpox. He turned out to be immune. Jenner explained Latin in his new way "vaccination" (vacca). But Jenner does not explain why this method worked well - at that time, it was not possible to see the virus with a microscope. He handed the document to the Royal Society the following year. It was somewhat interested, but I sought further evidence. Jenner continued immunization and surveillance for several other children, including his own son. The full result of his research was announced in 1798, but his obvious finding was satisfied even with a lot of dissenting opinions and even ridiculous. The value of his vaccine has been recognized over time, but because of limited access to medical care in many of the poor communities, all of his benefits were realized decades ago. Thirty years after Jenner's death in 1853, England and Wales began vaccinating against smallpox. British doctor Edward Jenner (1749-1823) began to be interested in the idea that diseases of vaccinia later protect people from smallpox. Jenna 's biographer insists that Jenner has heard the wisdom of this folklore from milk maid. Edward Jenner and the vaccine discovered John Hunter 's trained Edward Jenner (1749-1823) in London and was a military doctor for a while. After that he spent all his career in his homeland in Gloucestershire (Western England). His research is based on a careful case study and over 100 years clinical observation before scientists can explain real viruses and diseases. His innovative approach is successful ... Impact of tuberculosis vaccine Summary Tuberculosis is one of the most infectious diseases in the world. Since nearly one-third of the world's people are infected with this virus, efforts are being made to prevent the spread of this disease (NIAID, 2001). One of the preventive techniques for tuberculosis is BCG (Calmette and Guerin Bacillus) vaccine. In the early 20th century, Calmette and Guerin cooperated to isolate the diseased strains and developed the first BCG vaccine. Whole century Edward Jenner (1749-1823) succeeded in the initial smallpox vaccination and established an important milestone in vaccination technology. He is an English doctor who pointed out that milk maid influenced by vaccinia is resistant to smallpox. To take advantage of this finding, he was vaccinated by healthy boys infected with vaccinia and then attacked him with smallpox two weeks later (Figure 25.1). It is noteworthy that the boy was not affected by the smallpox attack. This suggests that previous pus exposure by vaccination prevented viral infection. Therefore, the efficacy of vaccination was first demonstrated. In retrospect, this human experiment is unethical today without proper approval.

Edward Anthony Jenner, also known as "father of immunology", is a British scientist known for the discovery of smallpox vaccine. This is the first successful vaccine developed so far and continues to be the only effective prophylactic treatment for fatal smallpox. His discovery was a major medical advance to save countless lives. In 1980, the World Health Organization announced that smallpox is a disease of eradication. In 1770, after completing 7 years of training as a surgeon in Gloucestershire State, I went to St. George's Hospital under the guidance of prominent surgeon John Hunt. Study anatomy and surgery. After finishing his research, he returned to Berkeley to establish medical practice until his death. Jenner and his colleagues read the paper on medical science in Gloucestershire State Rodderboro and founded the medical community to eat together. He also published useful papers on angina pectoris Jenner works in rural society. Most of his patients are farmers or work on cattle farms. In the 18th century, smallpox was considered the most deadly and most persistent human pathogenic disease. Prophylaxis of smallpox by immunization brought success to the Dutch physiologist Jan Ingenhaus and was brought to the UK by Mary Wortly Montague, Mrs. British Ambassador to Turkey in 1721 in the UK. This method is well known in eastern countries and involves scratching the veins of a healthy person and pushing a small amount of material (from a small pustule of a mildly attacked person) into the wound. The risk of treatment is that patients often infect complete diseases and lead to fatal consequences. In 1788, the wave of smallpox infiltrated Gloucestershire State, treated with cattle in outbreaks, patients infected with lighter disease vaccinia have never been infected with smallpox Absent. Jenner needs a way to prove that his theory is really effective. In 1796, Jenner conducted an experiment with one of his young patients, James Phipps, an eight-year old boy. After cutting James' arms twice, Jenner made a small amount of vaccinia for them. The boy showed normal reaction and showed a mild fever, but it got better soon after a few days. Several weeks later, Jenner repeated vaccinations and used the material of smallpox to keep the boy healthy. This is the way Jenner makes vaccinations, named after the medical names of vaccinia and vaccinia. In 1798, after a more successful test, he published his findings: Variolae Vaccinae, an investigation of the causes and effects of illness known as the name of vaccinia. Jenner was found to have a stroke in January 1823. He never recovered completely, and on January 26, 1823 he died of a 73-year-old stroke in Berkeley, Gloucestershire, England. In England, in the late 1790s, physician Edward Jenner discovered how to vaccinate people with smallpox vaccine. About 190 years later in 1980, it was declared that smallpox was eradicated (Edward Jenner). Today, humans continue to trace Jenner's footprints and continue working to treat and eradicate diseases threatening people all over the world. - Although vaccination has been in place for a long time, the controversy over these uses has declined significantly when the vaccine was first received. Over time, vaccines have been developed for diseases such as polio, varicella, varicella, and general influenza, as well as improvements and constant innovation. Prior to the development of the vaccine disease had become a big problem as it spread rapidly over a wide range. According to Harvard Medical School data, British rural doctor Edward Jenner produced the first vaccine in 1796. Jenner developed a small pox vaccine that changed the course of this deadly disease. Since then, many other researchers and doctors have developed other vaccines. When the vaccine reaches your child's health, the vaccine has both advantages and disadvantages, and some parents are working hard to make vaccination decisions. Using a vaccine can prevent you

It is difficult to imagine a world without a vaccine - the "disease" of the world has potentially deadly (body or at least irreparable damage of the cause). In this world, the disease has killed millions of bright child eyes. Fortunately, with the development of vaccines, the population has grown bigger and healthier in the past century. Sadly, despite improvements in our lives, many have not decided yet - or strongly disagree - children will be immunized. They claim that vaccination is dangerous and causes autism and other diseases. Today's medications are offered in several ways, including the use of needle and syringe vaccination. If the needle pain suddenly disappears, what will you think? Over the past several hundred years, medical advances have made wonderful progress, and we became a patient not to accept the point of injectable form of the liquid of the vaccine. According to Mark Kendall, an Australian scientist or biomedical engineer says it is stupid, his new invention Nanopatch has become an effective way of vaccination, which is cheaper than needle and syringe Is, the cold chain is more likely to be deleted It has the ability to improve immunogenicity In 1961, the bifurcated needle was developed as a more efficient and cost-effective alternative, and the main instruments used during exercise were eradicated from 1966 to 1977. Bifurcated needle vaccination requires only the quarter of the traditional method needed to carry out a simple amount of vaccine. Upon success in the production of the intensification eradication program used for smallpox vaccine, eradication of smallpox vaccine after the success by modern cell culture techniques to produce the end or the opposite of the stage known as the first generation vaccine Has been developed. Production of the same generation of smallpox and first generation vaccine or cloned virus as the same smallpox vaccine strain mutant The third generation smallpox vaccine purified from a conventional vaccine strain was used for eradication at the end of the stage It represents a more safe vaccine specially developed Further through cultivation and animal attenuated vaccine strains Currently, the official smallpox vaccine is a live virus prepared infectious vaccinia virus. Solution using bifurcated immersion vaccine (Nisata) vaccine needle management. A needle to puncture the skin (usually the upper arm) multiple times within a few seconds. If successful, a vaccine site or itching red clump will be displayed in 3 to 4 days. In the first week, the bump will be filled with pus (called "Jenner vesicles") big blister, will start the drain. In the second week, the blisters dried and started to scab. We will leave a small scar in the third week of the scab and fall

Little Pox Magazine April 22, 2005 - Since I have had a long week, I decided to write this article on an online magazine. After doing several papers, quizzes, and 40 hours of work, I got a bit bad weather. But most of us think this is because I am not asleep. But do not worry because I'm planning to make up for it on the weekend. But tonight I decided to go to a party and go to my apartment. Until then I will lie down drinking aspirin and going out. Small Pox & lt; Tab / & gt; Smallpox Virus & lt; Tab / & gt; Small Pox Vaccine is not manufactured or registered for use in Australia. Over 20 years ago commercial production of small pox vaccines in the world ceased. Edward Jenner found the first vaccine, the small pox vaccine so far. This vaccination resulted in effective protection of the disease by stimulating the production of antibodies against diphtheria toxin, a toxigenic strain of acne diphtheria, clostridium difficile. In Australia, the diphtheria vaccine exists in the form of DTP (diphtheria, tetanus and pertussis combined vaccine) at 2 months, 4 months, 6 months and 18 months after birth, and 4 to 5 years of age. In 1990, the World Health Organization said that 80% of children had been vaccinated against illness. Small variola is a big problem for the two fighters and ultimately brings benefits to settlers. Little pox spread through British and American troops, but Americans have developed a vaccination method - vaccine. They plunged to healthy people to take a little pox from the patient and to help their bodies learn to fight it as soon as possible so that their bodies can later fight the virus. Because of small pox, Britain could not find this way and soon lost soldiers. Their earlier advantage was British as they were shipping soldiers on board. Small variolas are truly deadly, but humans have weapons, ie vaccinia. In the late 1700's, Dr. Jenner noticed that dairy maid with mild vaccinia had never infected small pox. On May 14, 1776, he infected the boy named James Phpps with vaccinia and caused a small pustule. Then Dr. Jenner infected the boy with small pox, but he did not suffer small pox. Dr. Jenner found the only defense against small pox. This vaccine is very effective as there is no other smallpox host. This is the only owner who is a wise man. As a result, the World Health Organization launched a global plan to eradicate small variola, and they began vaccinating dozens of people. I am occurring, they go there to isolate people infected with smallpox, and vaccinate people around the area where the infected person was found. On December 9, 1979, Bangladesh reported the last case of small smallpox and therefore eradicated smallpox.

Range of state power affecting health: Jacobson vs. Massachusetts in 1905 v. Massachusetts Because the federal government has no clear authority to regulate public health, its regulation is based on the federal ability to manage interstate trade I will. As an example of this power there is a famous incident that the federal government prohibited buying food at the Southern Province fried chicken restaurant in the 1960s - we call it the Fried Chicken incident. . In the groundbreaking case in 1905, which later became the basis of the Public Health Act, Jacobson vs. Massachusetts State approved the US mandatory immunization law and approved the right to enforce 17. A lawsuit has been filed. At a public school in San Antonio, Texas (a later private school), the Supreme Court judged the school's vaccination requirements to be constitutional18. Required force Infectious diseases may not be considered when the US Supreme Court judge ruled in Massachusetts v. Jacobson in 1905. 109 As a precedent to establishing separatistic decisions, the majority of the High Court ruled that the Legislature could use police power to force small opposition citizens to use the smallpox vaccine. Judges at the beginning of the 20th century decided based on the wrong premise that they predicted that physicians would injured on behalf of public health authorities and would die of smallpox vaccination . The doctor was unable to predict exactly who injured and died of immunization More than 100 years ago, the US Supreme Court first discussed personal and public health priorities. In Jacobson and Massachusetts, Cambridge residents refused to vaccinate the smallpox vaccine as they believed that the law infringed the right to know their body best. The court dismissed Jakobson's challenge. This groundbreaking 1905 ruling is the basis for state actions to limit individual freedom to protect public health. Because public health regulation is aimed at protecting people as much as possible, there is tension, but we may prioritize group needs rather than personal preferences. In the case of vaccination, this task will sacrifice individual autonomy to protect the area from diseases. Individuals who are not vaccinated pose a risk to vaccinated children or medical contraindicated children or vaccinated individuals (vaccines are not 100% effective).

Edward Jenner, born in England in the mid 18th century, will eventually become one of the most famous scientists in medical history and become so-called "father of immunology." After observing that vaccinia infection can protect people from smallpox, Jenner was vaccinated with an 8 - year - old boy with varicella in the hands of British milk maid. Then he repeatedly tried to "challenge" immunization by exposing the boy to the material of smallpox - but that boy never got sick. Jenner proved its smallpox immunity Jenner's smallpox vaccination method became increasingly common and ultimately replaced the mutation that was the standard before his demonstration. About 150 years after Jenny died in 1823, smallpox will be the last gasping in the second half of the 20th century. After extensive monitoring and vaccination programs, it will eventually be eliminated - thanks to the initial efforts of the immunologist's father mostly thanks Edward Jenner's later years. Edward Jenner Museum. It is available from http://www.jennermuseum.com/Jenner/edwardjenner% 27sla.html. In short, Edward Jenner was one of the greatest discoveries in history, but his method and his data were flawed. Then his study was dismissed until vaccination was performed. Finally, Edward Jenner discovered that vaccinia can prevent smallpox, despite his lack of data and inaccuracy. When Edward Jenner introduced vaccination in 1796, there was a long history of immunization, a more primitive form of vaccination, including the introduction of deliberate diseases into the body. Like in Voltaire in the 18th century, the philosopher regretted his French attitude towards smallpox vaccination: in 1876, after a group of local representatives were elected anti-vaccination platform, they were riot I refused to enforce. Forced vaccines According to the London Times, these streets are "threatened because they are surrounded by a group of densely popular mobs, and the intention to rescue the prisoners is revealed soon". Despite the dangerous side effects, the vaccine history began with the vaccination of smallpox developed by Edward Jenner, as it is necessary to vaccinate more sites. 42 states have an essential vaccine policy, and many children must be vaccinated with at least 22 vaccines before first grade. Vaccination is a topic controversial among medical professionals as there is a possibility of health risk. Immunization is actually Immunization is designed to help people survive their daily lives. Eddie Jenner, a rural doctor who lived in Berkeley, England, began immunization in 1796 (Ministry of Health and Welfare). Throughout history, vaccinations are getting better for safer people. To maintain good health, everyone should receive vaccinations against certain diseases. Vaccines have been shown to immunize people to heavy sickness (child immunity). - Every year, thousands of Americans die of seasonal influenza. With this amazing statistic, the U.S. government strongly urged domestic and its children to vaccinate during the upcoming influenza season in November.