Ottawa Research Use Model (OMRU) is an interaction model developed by Logan and Graham (1998). OMRU considers the use of research as a dynamic process of interrelated decision-making and behavior by various individuals associated with each model element (Logan & Graham, 1998). The OMRU contains six key elements: (1) evidence-based innovation, (2) potential hiring, (3) practical environment, (4) implementation of interventions, (5) adoption of innovation, And (6) Innovation in execution results (Graham & Logan, 2004).
The purpose of this study was to determine the acute effect of inhaled salbutamol on heart rate, pulse pressure and maximal expiratory flow rate and to compare the effectiveness of salbutamol's metered dose inhaler (MDI) administration with quantitative salbutamol. The dose inhaler is connected to a gasket (MDI-gasket). The effectiveness of the two salbutamol delivery methods was analyzed by comparing the cardiovascular effects of bronchodilators and albuterol in subjects taking MDI and MDI spacers. Eighteen subjects were randomly divided into three groups of placebo, MDI, and MDI spacers. Subjects in the placebo group used a placebo MDI inhaler that served as a control. Subjects in the MDI group used salbutamol MDI. In order to administer the standard dose of salbutamol, they exhale completely, then slowly inhale through the opening as the drug is released from the MDI and then hold the breath for 10 seconds.
A metered dose inhaler (MDI) is used to treat asthma or other lung diseases. The inhaler delivers the drug directly to the lung where it can be quickly and completely absorbed at the desired site. MDI is designed to supply the lung with a precise or quantitative dose each time the lung is used. The metered dose inhaler can be used alone or on a spacer prior to inhalation. Inappropriate management means that the medicine is wasted and that person may not be able to benefit from that medicine