Using Germ-Line Therapy to Combat Disease

Please use germline therapy to fight disease in a world without disease or cancer. This can be achieved by germline therapy. By changing the chromosome before the child is born, diseases and cancers can be eliminated between generations. Target summary article Over the past four billion years, our lives have undergone various changes. These are genetic modification and natural selection. Genetic engineering offers many possibilities: now species can change their DNA.

Germline gene therapy involves altering the genes of ova cells or sperm cells and then passing genetic changes to offspring. Despite its potential to prevent hereditary diseases, this treatment is still controversial. Germline transmission of undesirable traits can now be prevented by preimplantation genomic diagnosis and then germline gene transfer remains open only for potentiation and this is considered unethical . However, in performing chemotherapy and clinically suggested irradiation, unintended germline genomic alterations can not be ruled out or even predicted (semen is usually collected prior to such treatment And stored). Therefore, germline changes can be inevitable for whole body somatic therapy. In the case of these non-gene therapies, there is clearly a risk, and in experimental human gene therapy, a putative germline gene transfer problem,

To date, in clinical trials of tolerable gene therapy, somatic cell therapy using disease-causing genes has been performed. However, many ethicists say that as more genes are found that result in different traits, with improved feasibility of germline gene therapy, "gene landslides" in the future gene therapy experiments I am worried that it may have an effect. Specifically, there is concern that receiving germline gene therapy may lead to gene therapy to enhance heredity. As scientific progress adequately recognizes the validity of these new treatments and must provide ethical guidelines for the advancement of gene therapy research, gene therapy that promotes germline gene therapy and trait enhancement The unresolved argument about the problem must be continued. The main participants in the open discussion came from the fields of biology, government, law, medicine, philosophy, politics, and religion.