Understansing Haemophilia

Introduction of Hemophilia Hemophilia is a term used to describe a range of hereditary hematologic disorders that have lifelong defects in the coagulation method. It is estimated that one in 5,000 people suffer from haemophilia. For those without hemophilia, the freezing point is like a series of dominoes like a causal reaction. If one of the factors is missing, the coagulation mechanism will not be activated. Haemophilia A, also known as Factor VIII, is a common defect of hemophilia.

How do people become haemophilia? Most of the haemophiliacs are men, but rarely females may also be affected. Hemophilia is a sex-related inherited disorder on the X chromosome; you can not "catch" haemophilia and people are born with it. On our genes and chromosomes, we inherited two sex chromosomes labeled X and Y from our parents. The female inherited two X chromosomes. The male inherits the X chromosome from the mother and inherits the Y chromosome (instead of the second X chromosome) from the father to a man. If a person has a haemophilia gene on its X chromosome, that person becomes haemophilia, but because there is less possibility that there are haemophilia genes on the two X chromosomes, there is haemophilia in the woman. It is not common. When her mother is her mother and her father is suffering from haemophilia, few women with haemophilia are born. These women are called carriers

There are mainly two types of haemophilia. A and B. Hemophilia A is also known as Factor VIII, but is a hereditary disorder caused by deficiency or deficiency of factor VIII (coagulation protein). (National Hemophilia Foundation, no appointment). Hemophilia B is also known as Factor IX (Christmas disease), but is a hereditary disorder caused by the deficiency or deficiency of Factor IX (coagulation protein). It is a gene by change. The X and Y chromosomes are called sex chromosomes. The hemophilia gene is on the X chromosome. Men have an XY chromosome, X comes from a mother, and Y comes from a father. Females have two X chromosomes, one from the mother and the other from the father. In this case, if a boys' mother has a hemophilia gene on the X chromosome, he develops hemophilia. However, the father can not pass hemophilia to his son. (National Hemophilia Foundation, no appointment). (National Medical Library 2012)