Therapeutic Angiogenesis for Brain Ischemia: A Brief Review

Needless to say, the movement involves brain function through many factors including stimulation of angiogenesis (generation of new blood vessels), neurogenesis (generation of new neurons), synapse (generation of new synapses), and generation of what is called a neurotrophic factor It improves. Brain Growth Factor One well-studied marker neutrophil is called brain-derived neutrophil factor (BDNF). BDNF is a protein called "Miracle Brain" by Dr. John J Ratey, a psychiatrist at Harvard University. BDNF is known not only to stimulate the growth and differentiation of new neurons but also to support and maintain the survival of existing neurons and neuronal pathways. According to Neuroscientist Dr. Brant Cortright, 60-70% of new neurons formed by neurogenesis were eliminated before being incorporated into our neural network. BDNF plays an important role in helping preserve these newly formed neurons.

The following comment clarifies some of these aspects and introduces the latest findings in this exciting field. Most of the data are obtained from animal experiments but all reviews are done with reference to human brain findings and induce plasticity after ischemia and finally the neurologic outcome after functional stroke Suggesting a potential new therapeutic strategy to improve. The review of this series begins with an article by Liu, Lang, Dempsey, Baskaya, and Vemuganti, which updates the potential of neural stem cells to repair brain damage due to stroke. After that, the role of angiogenesis after cerebral ischemia is discussed in a paper by Beck and Plate. Finally, my review reviews the neuroplasticity after ischemic preconditioning and the potential clinical similarity after transient ischemic attacks.