The Virulent Factors of Bordetella Pertusis

Pertussis is a highly contagious and acute respiratory disease caused by an aerobic Gram negative nonspore-encapsulated coconut bacillus, Bordetella pertussis. It is a strict human pathogen without known animal and environmental reservoirs (Cotter and Miller, 2009) and is infected by inhalation of bacterially infected water droplets. Therefore, colonies are formed in the ciliated cells of the bronchial epithelium leading to disease (Relman, D. A, 1995). Bordetella pertussis is characterized by excessive secretion of mucus, epithelial damage and pulmonary edema, paroxysmal cough for 1 month, and vomiting after cough.

Bordetella pertussis is a differential bacterium with a specific colony morphology. On the agar plate, the colony was small, and it appeared shining intensively. Bordetella is a Gram negative aerobic cocci that can exist in pairs or separately. Through the process of breathing and classification, Bordetella pertussis is metabolized, but it does not pass through fermentation. Bordetella pertussis does not belong to a specific family, but Bergey's Manual classifies it as "gram negative aerobic bar and cocci". Medium rich in medium with Bordetella pertussis is highly nutritious. Synthetic media containing buffers, salts, amino acid energy sources and growth factors can also be used to propagate Bordetella pertussis. The growth of bacteria is slow even on blood agar, it takes 3 to 6 days to form needle colonies during the growth phase.

The pathogenic factor of Staphylococcus aureus is a major component of life-threatening diseases. It is mainly the medium released by the immune system to give symptoms of the disease. Mutations in these pathogenic factors will reduce their toxicity to bacteria as these pathogenic factors do not target neutrophils, macrophages and other immune system components, and the symptoms of the disease will be alleviated It will be. Therefore, inflammatory mediators are not immediately released in large quantities.