The Tragedy of Xenotransplantation

The tragic background and challenges of xenotransplantation In 1954, surgeon Joseph Murray revolutionized the medical industry by first human organ transplant, that is, kidney transplant between the same twins (1). Initially, allogeneic transplantation was somewhat disturbed by the ability of the human immune system to reject foreign bodies. The introduction of cyclosporine, a potent medicine that minimizes the rejection of foreign bodies, greatly increased the likelihood of allogeneic transplantation (3).

Xenotransplantation is the process of transplanting or injecting living cells, tissues or organs from an animal into a human patient. Xenografts have been proposed to reduce the waiting time for transplanting organs to recipients who are unable to receive human organs because they were excluded from the transplant list or to wait for a person to receive an organ There.

A relatively new transplant sector revived this argument. Transplantation of xenografts or organs of animals (usually pigs) to the human body is expected to create many unique ethical issues while eliminating many ethical issues. Although xenotransplantation is expected to greatly increase the supply of organs, the threat of organ transplant rejection and the risk of heterologous seed disease combined with the general curse of the thought diminish the function of the technology. Several animal rights groups oppose sacrificial animals for organ donation and are implementing a campaign to ban them

Human xenografts provide potential cure for end-organ dysfunction, major health problems in some industrialized countries. It also poses many new medical, legal and ethical issues. A constant concern is that many animals, such as pigs, have a shorter life span than humans, which means their organization ages at a faster rate. Permanent changes in disease transmission (foreign body disease) and animal's genetic code are also gaining attention. Several cases of transiently successful xenotransplantation have been published