The Second Worldwide Killer: Cancer

The mouse double dual microhomolog (MDM2) enzyme, a negative regulator of p53, has been over-expressed up to 100-fold in various tumor cells for evaluation. A prodrug is an inactive or low activity molecule that is converted to an active drug by chemical or enzymatic biotransformation and is a potential drug such as insufficient site specificity, low absorption rate, and undesirable distribution Or due to poor drug candidate characteristics. Short-term toxicity and short-term effects, prodrugs should be considered as potential solutions for early drug design and development

Background: Breast cancer is the most common female malignancy in the world, accounting for 23% of all newly diagnosed cancer cases. It is also the leading cause of cancer mortality, accounting for 14.1%. In Zambia it is the second of cervical cancer, its incidence is steadily rising. Regardless of staging, cancer diagnosis is a stressful event that affects all aspects of the patient's life and the care of the family caregiver. In order to minimize the impact, an adaptive response mechanism is needed. Materials and Methods: A comprehensive review of the publications of Pub Med, Hinari, UK National Index, and African Journal cited from 1980 to 2010. The search terms include "stress", "c", "breast cancer", "binding mechanism", and "treatment mechanism of breast cancer patients and home care workers".

Breast cancer is a major fatal disease for the world and for women in this region. This is the most common cancer among women and the second most common cause of death among women in the world (World Health Organization, WHO, 2010). The incidence of breast cancer in women is still high. It is estimated that one million women per year suffer from breast cancer and approximately 519,000 women die of breast cancer (WHO, 2010; McPherson, Steel, & Dixon, 2000). According to Manning - Walsh (2004), the incidence of breast cancer is rising, and this event is fruitful for women of all ages, relationships such as marriage and sexual relations are affected. Negative Impact Stephen (2009) explained breast cancer as "malignant (cancerous) proliferation from breast tissue, a disease that proliferates in a way that abnormal cells are not controlled" (page 1). Breast cancer can be divided into four stages. 2002)

Breast cancer is a cancer that develops from breast cancer. It is a female murderer. "Breast cancer is derived from breast cancer, breast cancer is the second leading cause of death from women's cancer." (Breast cancer) Even though women are at high risk, anyone can become breast cancer . In the above article, "Most cases occur in women, but males also develop breast cancer" (breast cancer) There are several powerful ways to prevent breast cancer and reduce the number of deaths. This article states that the incidence of breast cancer has been increasing over the long term since the early 1970s, even if advanced testing is permitted (that is, whether conventional mammography has been introduced) Overall mortality rate Began to decline in the mid-1990s. "(Breast cancer (breast cancer. (Breast cancer.