The Role of the Lesion Method in the Understanding of Healthy Brain Functions

Understanding the relationship between brain and behavior is a complex phenomenon in the field of neuropsychology. In order to study the influence of brain function on human behavior it is necessary to adopt a method that can analyze various aspects of mental function. Therefore, this paper discusses the pathological method which is one of methods to evaluate the brain functions of humans and animals other than humans (Banich, 2004). The basic idea of ​​the lesion approach is to determine the correlation between lesions in specific areas of the brain and occurring behaviors.

Lesion research - still one of the most important ways to detect the secret of the brain. Neuroscientists use this knowledge to find out which parts of the brain are involved in which functions, when human beings and animals suffer brain damage (very local damage) and lose a very special psychological function You can map your existence. PET (positron emission tomography) - the process of scanning radioactive glucose in the brain. More specifically, glucose releases (or releases) positrons (antimatter, mirror image equivalents of electrons), which disappear as soon as they encounter electrons and emit a bundle of gamma rays picked up by the detector.

Lesion - a classical way of naturally or intentionally destroying the area of ​​the targeted brain, in order to observe the resulting change, such as a decline or improvement in the performance of a particular behavioral measurement. Damage to the atlas "thanks to the various brains" that provides a map of the brain region in three dimensional stereotactic coordinates can be placed with relatively high accuracy. It enables spatial and temporal control of G protein signaling in vivo with a receptor ligand (injection - synthesis ligand (RASSL) or receptor activated only by Designer Drugs (DREADD) activated receptor. These systems are designed using G protein-coupled receptors (GPCRs) for the synthesis of small molecule ligands such as clozapine N-oxide (CNO) rather than natural ligands. RASSL stands for GPCR-based chemical tool. These synthetic ligands can reduce neurological function via activation of G protein upon activation. It can weaken nerve activity through potassium