The Potential Impacts of Olfactory Loss on Our Lives under Different Situations

Introduction For thousands of years, people tend to think our sense of smell as natural. We named blind blinded patients blind people, lost their hearing as a hearing impaired, and lost their sense of smell. Olfactory is defined as olfactory dysfunction including partial obstruction and complete obstruction. Due to the complex relationship between taste and our brain, especially the limbic system, it is sometimes unimportant, common but sometimes devastating. This article shows the potential impact of olfactory loss by describing the process of perceptual olfactory and then analyzing the corresponding results.

Occlusion of nose and infection may temporarily lose smell. Conversely, olfactory permanent olfaction may be caused by nasal olfactory receptor neuron death or brain injury where the olfactory nerve is damaged or the brain area to treat odor is damaged. The lack of olfactory sense at birth is usually due to genetic factors and is called congenital olfactory loss. The somatosensory system is a complex sensory system composed of many different receptors, including thermal receptors, nociceptors, mechanoreceptors and chemoreceptors. It also includes a basic processing center, or sensory aspect such as proprioception, tactile, body temperature and nociception. Sensory receptors cover the skin and epithelium, skeletal muscle, bone and joint, viscera, and the cardiovascular system.

Our olfaction and smell have a very important effect on our health and health. This is because our sense of smell is activated when we inhale the smell from the nose. This is the only sensation directly related to our limbic system. The limbic system is called "emotional center" of our brain and supports emotion, behavior, and motivation. There is amygdala in the limbic system of the cerebrum. This is also called the "smoke detector" of the brain and activates the fighting / flying / freezing reaction. Even in the absence of fire, have you ever cooked in the vicinity of a "sensitive" smoke detector? This happens in the "smoke detector" of the brain when we are caused (by seemingly) by a mild stimulus. The limbic system is also home to the hippocampus, and the hippocampus is the brain area responsible for strengthening memory.

The mechanism underlying the current study may involve neurodegenerative changes in the olfactory bulb and brain area involved in memory and olfaction 38 Olfactory bulb occurs only in neurodegenerative diseases with olfactory pathology such as AD and Pa It is thought to be. The pathological marker of neuropsychiatry 39 AD (neurofibrillary tangle) is observed in the olfactory bulb and large fragment before the manifestation of symptoms associated with AD dementia, and the possibility that olfactory disorder is an early marker of AD risk Suggested 38, 40, 41. Presence of AD pathology in the olfactory cortex, hippocampus, and other temporal regions makes it impossible to save and retrieve olfactory memory for correct odor recognition. 42, 43 Cholinergic Defects Induced by Multiple Mechanisms Including Basal Nuclear Injury (Important Choline) It can be nuclear projection to brain regions involved in olfaction, involving olfactory loss in AD dementia and Parkinson's disease.

Relationship between olfactory dysfunction and amnestic mild cognitive impairment and Alzheimer's disease dementia