The Increase of Drug-Resistant Microbes

The increase in drug-resistant microorganisms over the past two decades is hurting the current efforts to combat infectious diseases. Due to increased tolerance to existing drugs, diseases that were thought to be managed in the past become a new threat, making other difficulties more dangerous: tuberculosis, pneumonia, malaria, cholera and HIV. Antibiotic resistance affects both developed and developing countries, but the impact on developing countries is much greater. The problem is that the price difference between inexpensive first-line drugs and second-line drugs is large, which means that most of the population can not access the original drugs.

Antimicrobial resistance to drugs: Drug resistance urinary tract, respiratory and skin infections are increasing. Treatment of malaria, HIV, tuberculosis is becoming increasingly difficult due to resistant bacteria. As a result, medical expenses are increasing. Taking organ transplant and cancer chemotherapy is becoming increasingly dangerous because of the increased risk of infection and the inability to obtain potential treatment options. Increase in extreme: Despite advances in technology and information, the world is becoming more conservative and extremist. Clearly, people are more affected by tribal and group thinking. Look at the rise of populist nationalists in Europe, America, South Asia, China, and Japan. And please do not talk about the Middle East and Africa. More body and mind walls are made. Do you tend to be extreme using dangerous modern technology tools?

Antibiotic-resistant microorganisms are a major problem for human and world health. One of the characteristics of microorganisms that allows the development of resistant mutations is the large number of microorganisms that live in a short development time and in a particular niche. Large populations may accumulate a small number of individuals with random genetic variation and these random mutations generally should give the benefit that microorganisms maintain within the population. A general understanding is that drug-resistant mutations need to establish drug exposure. However, in new antibiotic and chemotherapy studies evolution of drug resistance mutations in bacteria that have never been exposed to drugs has been reported.