The Effects of Social Interaction and Odor Exposure on Food Preferences in Sprague Dawley Rats

Mice habitat varies, and as a result, mice become skilled omnivores. Due to environmental diversity and subsequent diversity of potential foods and poisons in this environment, mice must eat selectively and carefully which foods. In addition, due to the anatomical limitation, rats can not vomit poisons ingested via vomiting. Therefore, rats must be adapted socially and behaviorally to reduce the potential hazards in the environment.

Sprague-Dawley rats (ca. 30 / group) of cecal contusion injury (not shown in summary) exposed to high intensity low frequency sound decreased adhesion formation from 83% incidence of control rats to 23% . Exposure to complete 12-day infrastructure sound. The effectiveness of the prophylactic effect thought to be caused by induced microtremors of abdominal organs increases with increasing duration. The induced motion clearly suppresses the formation of spun fibers. Rats did not show side effects of very low frequency therapy

Young male Sprague - Dawley rats (n = 16, age 23-27 days) and young adult male rats (n = 15, age 70-125 days; Harlan, Indianapolis, IN, USA) were used for the experiment . Rats were housed in standard cages. The house is at 12: 12 hours light / dark cycle (lighting at 10:00), room temperature control device (room temperature 21 ℃ 1). All behavioral tests are done at the beginning of the light. Please provide food and water freely. All animals were treated according to the Laboratory Animal Management and Use Guide, 8 th Edition. (2011). All procedures are approved by the University Animal Experiment Committee (IACUC)

According to OECD No. 414, pregnant female Sprague Dawley rats are forced to l, 4-diaminopurine at dose levels of 10, 40 and 160 mg / kg / day body weight on days 6-15 of gestation Orally. Only the vehicle was administered to the control group and swollen with 0.5% carboxymethyl cellulose (CMC) water. Animals in pregnancy are killed on the 20th day of pregnancy and viscera and skeletal malformations are recorded in the fetus. Female mortality was not recorded during the study. However, significant maternal toxicity was observed: weight gain and decreased food consumption from day 6 to 11. In the external examination, six fetuses from one high-dose group of dams had severe systemic subcutaneous edema associated with discolored placenta. In bone examination, it was noted that the basic cost of the lumbar spine was slightly higher in all dose groups.