Thalidomide

# Talidomide is a controversial medicine from the mid-1950's to the latter half. Since launch, I have witnessed the highest and the lowest. From destructive birth defects to the treatment of life-threatening cancers, thalidomide can be considered as Jeckel and Hyde in the pharmaceutical industry. The problem the pharmaceutical industry is currently questioned is that the risk of potentially devastating birth defects that can occur in the weather is worth the possibility of saving lives.

Thalidomide is a popular medicine used as a sedative by many pregnant women in the 1950s and 1960s. - Side effects of drug Psilocybin There have been many experimental and personal testimonies documenting the changes and effects of drug users of Psilocybin from ancient history to more modern side effects. For example, the Aztecs believe that they can come and go between the earth and supernatural (Schwartz 1988).

In the 1960 's, morning mitigation was relieved when the doctor came to give thirsty thalidomide to pregnant women. This medicine was immediately discovered that there was a serious congenital deficiency in infants born from women who took thalidomide during pregnancy. At that time, clinical trials in the United States did not require approval or supervision by the FDA. Therefore, thalidomide was distributed to more than 20,000 patients nationwide, of which about 207 were pregnant women. This is an event that led to the approval of Kefauver-Harris drug correction. Still, even now there are strict guidelines, sometimes

In the 1950s and 1960s, thalidomide was used to alleviate morning sickness during pregnancy. Unfortunately, thalidomide has a very bad influence on the uterus. Many babies die and about 15,000 babies are born with limb defects. Thalidomide has been tested on animals and I believe that many people can say that animal testing does not go well. However, it is rarely known that not all the necessary tests have been done. Because of these imperfect trials, the US Food and Drug Administration (FDA) has not approved the sale of thalidomide.

In fact, the tragedy of Thalidomide was caused by inappropriate animal experiments. It was not a standard procedure to administer medications for pregnancy before clinical use. If researchers notice the effects of thalidomide mutation, the results are confirmed in experiments using pregnant animals, and these tests will become standards for preclinical testing. Even after genetically engineering, there is no animal model that can accurately reproduce complex human condition. There are too many unknown variables that can not be explained sufficiently. Instead, there are scientific (non-imaginary) technologies such as microfluidic chips and microdoses. In addition to analyzing the effects of drugs on the whole life system, these techniques analyze human life systems, eliminate errors due to species differences, and generate data on humans.