Tay- Sachs Disease

Tay-Sachs is an inherited disorder located on chromosome 15. It occurs when the body lacks proteins that help destroy nerve tissue. It was discovered by Dr. Waren Tay and Dr. Bernard Sachs. Neurologist Dr. Bernard Sachs discovered the first explanation of the change in Tay-Sachs cells. He also found a pattern through which Tay-Sachs may spread through family connections, and more often through the east population of the Jews (then). In 1881, an ophthalmologist Dr. Waren Tay found a vivid cherry red circle on the patient's retina.

Tessa disease Disease disease is a fatal disease affecting the human nervous system. Tay-Sachs disease is a hereditary disease transmitted from the parent to offspring because there is no protein called hexosaminidase A in the body. Protein hexosaminidase A contributes to chemical degradation of gangliosides and other phospholipids found in nerve tissue. Tay-Sachs disease is caused by defective genes on chromosome 15. According to McKenzie (2009), Tay-Sachs disease is caused by excessive accumulation of ganglioside cell membranes in nerve cells in the brain, resulting in aminohexosaminidase A activity deficient protein. Tay-Sachs disease usually develops when a baby enters the womb, develops rapidly after birth, and dies when that baby is 4-6 years old. In the months after birth, infants with Taza's disease develop complications more than usual and die within 4 to 6 years. The treatment of disease is not known

Juvenile Tay-Sachs disease. Juvenile Tay-Sachs disease is rarer than other forms of Tay-Sachs and is usually seen first in children between 2 and 10 years of age. People with Tay-Sachs disease develop cognitive and motor skills, dysarthria, difficulty swallowing, ataxia, and paralysis. Death usually occurs between 5 and 15 years old. Adult / late-onset Tay-Sachs disease. The rare form of this disease known as adult onset or late onset manifests the first symptoms in the thirties or forties. Contrary to other forms, late-onset Tay - Sachs disease is not usually fatal, as it may result in ineffective progress. It is often misdiagnosed. It is characterized by gait instability and progressive neurological deterioration