The 2003 SARS epidemic caused new laws and policies on epidemics in the affected countries. The biggest change in health and epidemic policy happened in China, where the SARS virus seems to have started. In China, information on SARS is initially confidential so as not to damage Chinese trade and images. Therefore, the occurrence of the SARS virus enters Beijing and gradually becomes a threat to the health of the people. When SARS becomes a domestic and global problem, the Chinese government has launched a campaign against SARS.
Unlike SARS coronavirus, MERS-CoV differs from common cold coronavirus and known endemic human beta coronaviruses HCoV-OC 43 and HCoV-HKU 1. Until May 23, 2013, MERS - CoV was often called SARS - like virus, or simply new coronavirus, but it was widely called "Saudi SARS" in the past. As of 2017, more than 2,000 cases of MERS with a death rate exceeding 30% have been reported. By 2015, 182 genomes were sequenced (94 from humans, 88 from dromedary). All sequences are> 99% similar. The genome is divided into two branches, A and B, and in most cases it is caused by clade B. Mix with human camel species
Both SARS and MERS coronaviruses are closely related to bat coronavirus, suggesting that both viruses may be derived from bats. It is believed that SARS virus spilled from bats and struck cats and humans. The MERS virus is believed to have been spilled from Egyptian cave bats to humans and camels as intermediate host species. Heterogeneity of these viruses known as zoonoses spreads to make them more serious. Our immune system also does not have any memory immunity against these viruses, so infection may become more prevalent before control. This is particularly problematic for the elderly and other people with health problems - indeed, these patients are experiencing the effects of MERS coronavirus infection
Sometimes, the zoonosis infection virus can jump directly into the body like the Marburg virus. Other viruses, such as viruses that cause SARS, will first flow out from wildlife species to livestock. Viruses proliferate and evolve, increasing the infectivity of human hosts. Various things happen when zoonotic virus infects humans. If it is extremely toxic it will immediately kill that person's host - from a strict epidemiological point of view this may be considered beneficial as the virus is less likely to spread to others . However, if the virus takes a while to make the patient sick and spread easily to others, even bigger problems arise.