Research Study on Interactions Between Genes and the Environment in the Causation of Chronic Disease

Regional residents were registered in the Multi-ethnic Group (MEC) of the Singapore Collaborative Research Consortium (SCCS). It began to study the interaction between genes and the environment in chronic causation (Chen et al., 2010). As a sub-group of SCCS, MEC is comprised of 9,000 community-based Singaporeans aged 21 to 75 and is recruited through public relations activities and introductions (SCCS, 2006).

Interest in research on gene - environment interactions (GxE) has attracted interest for the connection with the development of psychopathology. In this article, various approaches to study the interaction between genes and environment, an overview of methods for animal and human research, and the interaction between genes and the environment detected using these various methods This section explains. Genetic-environmental interaction studies investigating genetic effects of possible simulations (eg from studies of families, twins, and adoptions), and studies of measured genotypes were studied. Importantly, the rapid rise in interest in gene-environment interactions has led to the identification of various types of interaction distinctions, capacity and environmental measures with broad implications for detecting gene-environment interactions We raise many tasks.

This article first outlines various research designs used to detect the interaction between genes and environment while explaining the outline of animal and human research methods. I introduced gene-environment interaction studies investigating the genetic impact of potential simulation and genotype studies. In a study of potential gene-environment interactions, genetic influences are inferred based on correlations observed among people with different genetic and environmental share differences, although specific genotypes are not measured It was done. Therefore, potential gene-environment interaction studies investigate the collective influence of genes rather than any particular genes. In contrast, studies of molecular genetics usually focus on specific genes of interest at one time. I review epigenetics, a relatively new field of research that provides a potential biological mechanism by which the environment reduces gene expression and can affect behavior.