Progeria:The Aging Disease

Genetic diseases affect people throughout history. They bring harm and death to humans. In the Middle Ages, people will see some people die without knowing why. In the past 100 years, scientists began researching genetic diseases (quotations). An example of genetic disease recently discovered by scientists is premature. Premature aging is a rare genetic disease that can rapidly aging children. Millions of people worldwide are suffering from premature aging and 8 million people suffer from this disease every quarter.

Unlike other "aging-promoting diseases" (such as Werner's syndrome, Cockayne syndrome or pigmented dry skin disease), premature aging is not directly caused by DNA repair defects. Although these diseases cause changes in various aspects of aging, they often are called "segmented primary" because they do not cause changes in every way. Growth hormone therapy was attempted. Attempts have also been made to use morpholinos in mice and cell culture to reduce progesterone production. An exon 11 specifically mutated to the mutant pre-mRNA and an antisense morpholino oligonucleotide linked to exon 12

Premature aging is a very rare autosomal dominant disease and symptoms similar to aging appear at very young ages. Premature aging is one of several prostate syndromes. People born with premature aging usually live in their teens to early twenties. It is a genetic condition that occurs as a new mutation, and carriers are rarely inherited because they are not usually. The term premature aging applies strictly to all diseases characterized by premature aging symptoms and is often used in such diseases, but it is generally applied in particular to Hutchinson-Gilford early stage syndrome (HGPS) .

Premature aging, also known as Hutchinson - Guildford Premature Syndrome (HGPS), is a rare illness that causes children to get aged 8 times faster than expected. It was found in Britain in 1886 and was named after Jonathan Hutchinson who first discovered it and Hastings Gilford who first called for diseases known as premature aging. The name Progeria derives from the Greek word "premature". Early aging is often called "premature aging disease". Fortunately, this is a very rare illness. Only 100 cases have been reported since the discovery and it is estimated that 1 to 2 children out of 8 million cases are affected. Currently there are only 4 children in the UK and about 40 children worldwide. However, this is a particularly tragic disease, as it usually attacks children under 10 years old and usually dies around the age of 13. The average life expectancy of premature babies is from 7 years old to 27.5 years old.