Essay sample library > Portable Capilary Electrophoresis Insturment

Portable Capilary Electrophoresis Insturment

2023-06-28 20:06:36

Portable equipment for on-site analysis rapidly grows because of the availability of the results, elimination of complexity of sample storage and shipping, and more cost-effective than traditional benchtop analysis systems It is. Portable analytical instruments require compact size, light weight, durability and low power consumption, and automation of operation. Capillary electrophoresis (CE) separates a mixture into its constituents by a strong electric field applied across it. A thin capillary filled with electrolyte separates the solution due to the difference in fluidity of the stationary phase 2.

Electrophoresis has been highly diversified since the 1950's and new methods such as affinity electrophoresis, capillary electrophoresis, electroblotting, electrophoretic mobility shift analysis, isokinetic electrophoresis, pulsed field gel electrophoresis and Application is still under development. And preparative electrophoresis.

Electrophoresis began in the early 19th century and still in practice even after 2 centuries. Existing electrophoresis is done in many different ways and methods, but the equipment and style are very different from the original design, but the core principle remains the same. By tracking the trend of changes in electrophoretic technology, the next step will be the miniaturization and portability of the system.

The history of electrophoresis began with the work of Arne Tiselius in 1931, and separation process and chemical analysis technology based on new electrophoresis continued to evolve in the 21st century. With the support of the Rockefeller Foundation, Tiselius developed the "Tiselius Instrument" for moving boundary electrophoresis described in 1937 by the famous article "New Equipment for Electrophoretic Analysis of Colloid Mixtures". did. This method slowly became popular until effective area electrophoresis appeared in the 1940's and 1950's using filter paper or gel as a supporting medium. By the 1960's, increasingly complex gel electrophoresis made it possible to separate biomolecules based on small physical and chemical differences and served to promote the rise of molecular biology .