Poliovirus Introduction Poliovirus causing polio in humans is an enterovirus belonging to the picornavirus (small RNA) family. Polioviruses are fast, acid resistant, stable, highly tissue specific, composed of single stranded positive RNA. Poliovirus is found in human throat and intestine. Polio is a highly contagious infection with three viruses, poliovirus 1 (PV 1), PV 2 and PV 3. Although poliovirus is rare in developed countries, vaccination is not common and can be seen in many low-developed countries.
Poliovirus (scientifically wild-type poliovirus - WPV) invades the body via infected people's mouth, water, or food contaminated with feces. The virus grows in the intestine and is excreted by infected people in feces Hygiene is bad and the virus spreads to others. No, there is no cure for polio. Polio can only be prevented by vaccination with a safe and effective vaccine. Oral polio vaccine (OPV) is the only way to confirm that children are protected from polio. We encourage all children to complete regular vaccinations before the age of 1 and take additional doses during each exercise.
In 1955, in a tragedy called a cutter, the Cutter Institute accidentally administered 120,000 doses of soak polio vaccine containing several live polioviruses and inactivated viruses. As a result of this vaccine, 40,000 polio occurred, 53 were paralyzed and 5 died. This disease spread throughout the recipient's family, causing a polio epidemic, and 113 more paralytic polio and 5 more people died. This is one of the most serious pharmaceutical disasters in American history.
More than 100,000 children were injected misdirected alive, a dangerous poliovirus. To make matters worse, children who were vaccinated with the cutter spread the polio to others and began the epidemic of the first and only human polio. After the dust settled, the poliovirus contained in the cutter vaccine infected 200 thousand people, caused about 70 thousand mild polio, 200 people had severe paralysis, most of them were children; 10 A person died. Its episode-office is correctly described as "one of the most serious biological disasters in America's history" - in the early 1950s, remember in the context of polio. Hello. Today, for vaccination, the disease has been eradicated from the United States and has been almost eradicated throughout the world.