Pick's Disease

Pico disease is a type of dementia characterized by progress in social skills, irreversible deterioration and personality changes, and damage of intelligence, memory and language. In 1892, a German neurologist, Arnold Pick, studied patients with dementia and aphasia. When the patient dies, his brain contracts and brain cells die in certain areas of the brain (atrophy). In Picker's disease, the frontal and temporal lobes of the brain are most affected.

Pico disease (Frontotemporal dementia): Over the years, abnormal protein accumulation has destroyed a wide range of nerves in the front and side of the brain. Changes in personality, inappropriate behavior, difficult remarks, memory loss, and intelligence are symptoms. Pick's disease is progressing steadily. Alzheimer's Disease: For some unknown reasons, some brain areas degenerate, resulting in gradual loss of memory and mental function, behavior and personality change. Often called entanglements and plaques - accumulation of abnormal tissue in the brain area is considered the cause of this disease. Alzheimer's disease is the most common form of dementia

Degenerative changes in the limbic system may play a role in the development of neurodegenerative diseases, particularly Pick's disease and Alzheimer's disease. Significant atrophy was seen in the limbic system, most notably in the dentate gyrus and the hippocampus. In Alzheimer's disease, senile plaques and neurofibrillary tangles are scattered throughout the cerebral cortex and basal ganglia, but the hippocampus and amygdala are often affected severely. Studies have shown that the critical volume of schizophrenia patients decreases. The Papers circuit may be involved in schizophrenia. The evidence for this is distortion of the ERC layer II cortical neuron tissue, reduction of hippocampal volume, and reduction of the number of GABAergic cells in cingulate gyrus and anterior thalamus, resulting in glutamate excitotoxicity. Another circuit involved is the basolateral circuit that mediates social cognitive impairment in schizophrenia.

Pick's disease (also known as frontotemporal dementia) is a rare disease that occurs in the home and can cause deterioration of the frontal and temporal lobes of the brain. In some cases, this can be serious, allowing reasonably accurate diagnosis based on imaging. However, in most cases it is not easy to diagnose, especially at onset. This situation tends to be presented in one of two ways. First of all, it may act as an out of order behavior (usually invalidating behavior and indifference). Prohibited actions include excitement, social corruption, or impulses. Often there is lack of insight and lack of sympathy for their situation. The second type of performance is primarily a matter of language, usually accompanied by action problems. Despite these drawbacks, the memory and space skills remain intact. Pathology does not indicate a change in Alzheimer's disease, but rather indicates the presence of a "selected body" within a neuron.