Pharmaceutical Manufacturing: Prevention of Cross Comtamination

Prevention of cross contamination: Contamination is the presence of unnecessary substances on the surface and liquid There are several examples that cause contamination; people, raw materials, air, water. This should be prevented as it has a high risk of safety impact on the patient and should be considered from the design stage. By implementing, you can prevent this by monitoring and observing rules - SOPs must always be kept. - All SOP (GDP) changes must be recorded and recorded.

A clean room is an environment for manufacturers to prevent contamination by floating particles of products. Clean rooms are most commonly seen in the pharmaceutical and medical equipment industries. They are regulated by the US Food and Drug Administration. The FDA is issuing regulations, requirements, and recommendations on how to handle clean rooms. The FDA is demanding strict environmental management. The first is the plan and construction of a clean room that meets clean air standards. To monitor indoor air, a monitoring room separate from the clean room is required. This room requires equipment to manage clean room humidity, pressure, dust, temperature, and microorganisms.

Pharmaceutical microbiology is an applied field of microbiology. Minimize the amount of microorganisms in the process environment, microbial and microbial binary products such as exotoxins and endotoxins, microbial binary products, eliminate water and other raw materials, ensure the sterility of the final product, such as microorganisms related to the pharmaceutical industry Includes research. Other aspects of pharmaceutical microbiology include research and development of antiinfective drugs, use of microorganisms to detect mutagenicity and oncogenic activity in anticipated drugs, and use of microorganisms in the manufacture of pharmaceuticals such as insulin and human growth hormone .