Pathophysiology, Progression, and Treatment of Alzheimer’s Disease

Alzheimer's disease is dementia affecting the cognitive function of the elderly. The exact cause of this disease is unclear, but it may include genetic factors and environmental factors. Progression of certain neurological changes allows the progression of the disease. Short-term memory loss and dementia are typical symptoms of this disease. Confirmation of this disease can be confirmed only by autopsy. Disease progress is divided into 5 stages, each of which is different.

Pathophysiologic changes that occur in the brains of Alzheimer's disease patients lead us to a new direction of medical care. As the disease progresses, the brain begins to decay through atrophy (or atrophy), inflammation, increased free radicals, and mitochondrial dysfunction. When the balance between antioxidants and biological stress breaks down, free radicals are formed. That is why it is important to store foods rich in antioxidants. Foods derived from plants such as fruits and cruciferous vegetables are a good starting point. A big shell pizza just cuts it in a fight against free radicals.

Alzheimer's disease is thought to be a progressive multiple neurodegenerative disease, and it is a major cause of dementia in late adulthood. Pathologically, it is characterized by intracellular neurofibrillary tangles contributing to aging and extracellular amyloid deposits. In the past two decades, advances in the field of etiology have driven researchers to study new medications that further focus on the pathophysiological events of the disease. Currently available therapeutic agents, acetylcholinesterase inhibitors (rivastigmine, galantamine, donepezil) and N-methyl D-aspartic acid receptor antagonists (memantine) have minimal impact on disease and advanced aspects of disease As a target. These medicines slow down the progression of the disease and alleviate the symptoms, but can not obtain an obvious healing effect.

The method of diagnosing and treating Alzheimer's disease is similar to other forms of dementia. Unfortunately, AD can not cure, but there are many treatments that can delay the progression of the disease. According to the Alzheimer's Association, individuals diagnosed with AD have an average life expectancy of 4 to 8 years after diagnosis. However, individuals can live for 20 years after being diagnosed as ill. For more information on diagnosis of Alzheimer's disease and treatment of Alzheimer's disease, please click the following link.

Treatment of dementia depends on its cause. In the case of the most advanced dementia including Alzheimer's disease, there is no cure and treatment can not delay or prevent progression. However, medicine can temporarily ameliorate symptoms. The same medicine used to treat Alzheimer's disease is one of the drugs that may be used to treat other types of dementia symptoms. Non-pharmacologic therapy can also alleviate some of the symptoms of dementia. Several risk factors of dementia such as age and inheritance can not be changed. However, researchers continue to explore the impact of other risk factors on brain health and prevention of dementia. Some of the most active areas of research to reduce risk and prevent risk include cardiovascular factors, physical health and diet.