Nicotine

In today's world, nicotine is one of the most commonly used addictive medicines. The impact on society will differ. It is one of over 4000 chemical substances contained in smoke of tobacco products such as tobacco, cigars, pipes. This addictive medicine is the main ingredient of cigarette acting on the brain. There are two ways to smoke, it can be dry brown leaves of various sizes, or it can be a growing form of tobacco. When extracted from leaves, nicotine is colorless, but it turns brown as soon as it is exposed to air.

Nicotine is an effective parasympathomimetic drug and alkaloid found in Solanum. Nicotine acts as a receptor agonist for most nicotinic acetylcholine receptors (nAChRs), except for two nicotinic receptor subunits (nAChRα9 and nAChRα10) that act as receptor antagonists. Nicotine content in tobacco is 2-14%, and tobacco (Nicotiana tabacum, Duboisia hopwoodii, Asclepias syriaca) in tobacco plants. It accounts for about 0.6 - 3.0% of the dry weight of cigarettes. The concentration of nicotine at a concentration of usually 2 to 7 μg / kg (wet weight 20 to 70 ppm) is found in edible plants of Solanaceae such as potatoes, tomatoes and eggplants. The nicotine content of tea is very contradictory, and in some cases it is much more than the nicotine content of the fruit of Solanaceae.

According to the mainstream "nicotine hypothesis", nicotine is the main biochemical cause of smoking. Nicotine resembles an important neurotransmitter, acetylcholine. Other chemicals in tobacco smoke may promote nicotine intake. However, the nicotine theory can not explain the following contradictions: Other possibilities are the various neurotransmitter-like psychoactive aromatic amines (amphetamine, thiol-derived cannabinoids, elgin-type alkaloids) pyrolyzed during smoking . Thermal decomposition synthesis is random synthesis, aggregation is seen in various plant smoke. Nicotine itself can be used as a template for other psychoactive compounds