Neurological Effects of Fos B Gene on Behavior of Mice

The purpose of this study was to understand the neurological effects of fos B gene and mouse behavior by analyzing "lack of mouse lacking immediate early gene fos B" published on July 26 did. Cells Through various chemical and behavioral tests, fos B mothers found that they showed young people who could not train them. The results indicate that the lack of expression of the fos B gene in certain areas of the brain is a possible cause of the lack of culture response in mutant mice.

Researchers examined the anxiety and attack of mice lacking the Pet-1 gene and compared their behavior with normal mice. In the challenge test, we tested the mouse's response to invading mice entering their territory. Due to the anxiety test, researchers measured the time that the mouse remained in the open unprotected area of ​​the test room compared to the enclosed protected area. Researchers said normal mice would invade unprotected areas to explore, but mice lacking Pet-1 completely avoided this area, indicating abnormal anxiety behavior.

Since then, dozens of studies on mice have been done pointing out the effects of specific intestinal bacteria on mouse behavior and neurochemistry. Mice are used to facilitate experimental studies and the main way to isolate the action of bacterial strains is to use animals that breed, breed and maintain in a sterile environment. The result is truly incredible every time new stomach bacteria are introduced to observe the behavior of the mouse and the effect on neurochemistry.

More than a decade ago, scientists have shown how uterine changes affect mouse gene. They tested mice with mutations in the Agouti gene; this genetic change caused their skin to turn yellow and resulted in obesity and poor health. They gave methyl pregnant foods to these pregnant mice. Food changes the chemical environment (methylation) around the agouti gene of offspring. As a result, most babies have brown coats and normal weights 7 and 8 experiments did not alter their DNA, but the expression of the Agouti gene in them.