Mouse Pregnancy Lab Report

Mouse pregnancy experiment subject: Weight gain of pregnant female mouse and fetus. Question: How much does a female mouse increase in weight during pregnancy? Background information: Unlike humans, mice have multiple young people. The fetus grows through cells that divide at near exponential rate. The fetus develops most during the first semester. Hypothesis: If a healthy female mouse is pregnant and then excluded weight from simple growth, the weight is slightly below the index.

Scientists recently reported significant success in using IVG for mice. In 2016, Japanese scientists reported on the laboratory dish that the entire spawning cycle of the mouse could be reconstructed. They start with mouse embryonic stem cells or iPS cells and reprogram them into so-called primordial germ cells, which are sperm cells or precursors of egg cells. Then, these cells support the development of mouse eggs and mix with other cells that form ovaries in the plate. They found a way to add various hormones and other compounds to the culture dish and ultimately induce normal cell development into the egg cells. These eggs are fertilized with sperm and give birth to healthy mouse.

With transgenic technology, scientists can introduce foreign genes into early mouse embryos to create "transgenic mice" where one or more of the genes have been artificially and permanently altered . When Philip Leder's laboratory introduces the oncogene c-myc into mouse mammary gland cells, it produces only small tumors, usually tumors only occur after pregnancy, suggesting that hormonal effects play a role . Leder then made a transgenic line containing two oncogenes, ras and myc. These tumors are frequent, but Leder is confused as millions of breast cells acquired ras and myc, but only a dozen tumors