Metformin in patients with type 2 diabetes and kidney disease: a systematic review

Metformin should not be banned for patients with type 2 diabetes mild to moderate renal dysfunction

Metformin is considered to be the best initial treatment for lowering the blood glucose level of type 2 diabetic patients. Chronic kidney disease (CKD) is a common symptom of type 2 diabetes and may challenge the use of many hypoglycemic agents 2.

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A: As an endocrinologist, I take care of people with diabetes. Chronic kidney disease is a common complication of diabetes, and unfortunately patients with chronic kidney disease could not use metformin in the past. I have many patients whose renal function worsens over time and I have to stop metformin - it will cause their diabetes management to deteriorate. Metformin seems to be safe from the viewpoint of lactic acidosis of mild to moderate chronic kidney disease, but also seems to be associated with a lower mortality rate and it really seems that we enter the clinical setting I will help. I already have it - I was able to resume metformin for some patients who previously invalidated it

Diabetes - Chronic kidney disease is associated with type 1 and type 2 diabetes. Excessive sugar (glucose) accumulates in the blood if the patient's diabetes is not well managed. In the first 10 years of diabetes, kidney disease is rare; it is more common in 15-25 years after diagnosis of diabetes. Kidney Scan - Kidney Scans include magnetic resonance imaging (MRI) scan, computed tomography (CT) scan, or ultrasound scan. The goal is to judge whether the urine flow is blocked. These scans also show the size and shape of the kidney - the late stage of kidney disease, the kidneys are small and heterogeneous shapes