Insulin-producing Cells Derived from Stem Cells: A Potential Treatment for Diabetes

(2006), the possibility of circulating bone marrow cells is high and can serve as a precursor of various cells dispersed in the body. Cells other than true hematopoietic stem cells derived from bone marrow can be used as circulating stem cells or progenitor cells. Recently, it has been shown that bone marrow cells can cause impressive regeneration of liver tissue. Furthermore, bone marrow cells are not precursors, but cofactors that promote the formation of new beta cells, Bonner-Weir et al, 2006, p. 411).

"Why is stem cell important? Studies of stem cells are of great value in scientifically understanding the development of human beings and the possibility of treating the disease, many of which relate to the efficacy and safety of new drugs and treatments Experiments can be done with cell lines made from stem cells and by forming hepatocytes using stem cells to form functional liver and transplanting them to liver failure patients, It solves the problem of insufficiency and furthermore it can solve the immune rejection of the organ.The problem is that it is possible to make insulin producing cells using stem cells and transplant them to type 1 diabetic patients , That is, stem cells can cure many diseases such as liver disease, diabetes, Alzheimer's disease, Parkinson's disease etc. This list can continue for heart disease, spinal cord injury

Liver stem cells and stem cells. The status of adult pancreas and liver stem cells has not been clarified. Both tissues are derived from embryonic developing endoderm. Recent studies have shown that single progenitor cells derived from embryonic endoderm can produce ventral pancreas and liver. However, in adult mammals, both pancreas and liver contain various differentiated cells that can be repopulated or regenerated by different types of stem cells. In the pancreas, endocrine (hormone-producing) cells occur in the islets of islets of Langerhans. They include beta cells (which produce insulin), alpha cells (secrete glucagon), and cells which release the peptide hormone somatostatin and pancreatic polypeptide. Adult pancreatic stem cells are thought to occur in the pancreatic duct or the pancreatic islet itself. Stem cells and diabetes)