Inherited Diseases: Xeroderma Pigmentosum

These kits are currently in use and seem to be useful for protecting against ultraviolet rays. In addition to the suit, there is a night camp for them with XP. The Dermadilo camp in Texas is sponsored by the American Academy of Dermatology. In this camp, night activities are held in a building protected from ultraviolet rays (XP) so that children can have a good time to interact and have fun. In order for XP children to be able to send "normal living" even more, treatment is necessary to help them to improve themselves.

Pigmentary xeroderma (XP) was originally described by Hebra and Kaposi in 1874. In 1882, Kapoji created the term dry skin pigmentation, which refers to its characteristic dry pigmented skin. Pigmentary xeroderma is a rare illness that spreads in an autosomal recessive way. It is characterized by photosensitivity, pigmentary changes, premature skin aging and malignant tumorigenesis. These symptoms are due to cellular allergy to ultraviolet (UV) radiation caused by defects in DNA repair.

Pigmentary xeroderma, commonly called XP, is a hereditary disorder characterized by extremely high sensitivity to ultraviolet (UV) radiation from sunlight. This condition affects mainly the eyes and parts of the skin exposed to the sun. Some affected people also have problems with the nervous system. Symptoms of skin diseases usually occur in infancy or early childhood. Many affected children experience a bad sunburn after spending several minutes under the sun. Sunburn can cause redness and blisters for several weeks. Other affected children will not get tanned with minimal sunlight, but they will get sunburned. By 2 years of age, almost all children with pigmented skin develop skin freckles in places exposed to sunlight (face, arms, lips, etc); this type of freckle is rarely sick It happens to children. When exposed to the sunlight of the affected person, it usually becomes dry skin (dry skin disease) or skin pigmentation (pigmentation)

People with pigmentary dry skin diseases have a much higher risk of developing skin cancers. Without sunburn prevention, about half of children in this condition develop the first type of skin cancer at the age of ten. Most people with pigmented skin develop various skin cancers throughout their lifetime. These cancers occur mostly in the face, lips, eyelids. Cancer can also occur on the scalp, eyes and tongue. Studies have shown that people with pigmented dry skin disease may also suffer from other types of cancer, including brain tumors. In addition, the risk of lung cancer increases significantly in affected people who smoke.