Information of Macrocyclic Systems or Cyclophanes

Macrocyclic systems; other substances known as cyclic aromatics are the most important chemical compounds and biochemicals and pharmaceutical chemicals in the past few decades. Those roles in the understanding of molecular processes in many important roles such as biochemical systems, material science, encapsulation, catalysis, wet metallurgy, activation, separation and transport are important for their research and research in science and medicine Connected. More attention [1-8]. Paraquat type macrocyclic compounds have also been studied for their host-guest chemistry [9], redox behavior [10], catalytic activity [11], and incorporation into supramolecular structures.

Porphyrins are a group of organic compounds, many of which are found in nature. One of the most famous porphyrins is heme, pigment of hemoglobin. Heme is a cofactor for protein hemoglobin. They are heterocyclic macrocyclic compounds consisting of four modified pyrrolylene groups, in which alpha carbon atoms are bonded to each other by a methine bridge (= CH-). Porphyrins are aromatic hemoglobin (also known as hemoglobin, abbreviated as Hb or Hgb), a ferrotransport metalloprotein in vertebrate erythrocytes and several invertebrate tissues. Hemoglobin in the blood is the transfer of oxygen from the lungs or sputum to other parts of the body (ie tissues) where oxygen is released for cell use.

Anemia is a decrease in red blood cells or hemoglobin in the body (2). Hemoglobin is an iron-containing protein in erythrocytes. Hemoglobin binds oxygen molecules and transports them to somatic cells. Due to the small number of red blood cells, your body (including your brain) can not get enough oxygen and optimal function. Red blood cells are made of bone marrow and have a life of about 110 days, during which red blood cells circulate and supply gas to the body (3). As they get older, they eventually break down in the spleen, lymph nodes and the liver and some of them circulate in the body. Any damage (creation, functional life or destruction) in the life cycle of erythrocytes can lead to anemia. Common causes of anemia are as follows. Blood loss, parasitic infection, nutritional deficiency, absorption disorder and chronic disease (1, 2)