Inflammatory Indices and its Relevant Factors in Pregnant Iranian Women

Introduction C reactive protein (CRP) is an acute phase protein produced by liver tissue in response to tissue injury, infection and inflammation (1). Tumor necrosis factor alpha (TNF-alpha) is also an acute phase protein produced by macrophages and adipose tissue in response to inflammation (2-3). Pregnancy is associated with increased production of proinflammatory markers due to increased biosynthesis of pro-inflammatory factors (including TNF-α and C-reactive protein) in adipose tissue (4) and placenta (especially late pregnancy (5) It is relevant.

Early detection of asymptomatic bacterial urinary disease has great potential value for pregnant women and children, bacteriuria is an established risk factor for serious complications. Symptomatic urinary tract infection occurs in about 20 to 40% of untreated asymptomatic bacterial urinary disease. (58) The fetuses of these women are increasing the risk of preterm birth and low birth weight and later maternal chronic kidney disease. (39, 59, 60) Several randomized controlled trials have shown that treatment of asymptomatic bacterial urinary disease during pregnancy can reduce the incidence of symptomatic urinary tract infections and premature labor. (39, 61, 62)

Pregnant women Pregnant women with asymptomatic bacteriuria have a higher risk of acute pyelonephritis in second or third semester. Therefore, they need to handle this situation by sifting. In this guideline we recommend that you conduct asymptomatic bacterial urinalysis on pregnant women during pregnancy at pregnancy 12 to 16 weeks or during the first consultation after pregnancy. E. coli (E) Escherichia coli occupies over 80% of all UTIs, females, especially young women, in most cases cases of simple cystitis. E. coli is a harmless microorganism usually derived from the intestinal tract. It is usually contained in feces. E. coli strains causing UTI have special properties that make them more easily survive and infect the urinary tract. These strains are called urinary tract pathogens. If pathogenic E. coli (UPEC) spreads through the vaginal opening, it may invade the bladder to form colonies and cause infections.