Infection

Infections - Part 1 I will softly lie next to me. I rolled toward myself and opened my eyes. It is fuzzy that everything is out of focus. Like a camera not in focus. After a while, everything became a focus. I did not miss it. Most furnace rooms are as dark as the night, except that the light bulbs are blinking. I did not actually understand what was going on, I left the furnace room. The house is very quiet. I was confused and hurried down the stairs and headed to the kitchen.

Infected children with severe myelosuppression may be infected. Bacterial infections are the most common. Viral and fungal infections can be life-threatening. Infection may prolong the hospitalization period, hampering or delaying implantation, and / or causing permanent organ damage. Antibiotics, antifungal drugs, antiviral drugs are commonly used to prevent severe infections in immunosuppressed children. There are few platelets and few red blood cells. Thrombocytopenia (low platelets) and anemia (low red blood cells) are dangerous and even life threatening because the bone marrow does not function. Most children require multiple blood transfusions. Less platelets can cause dangerous bleeding in the lung, the gastrointestinal tract (GI), and the brain.

Bone marrow transplantation is a medical procedure used to replace bone marrow that has been damaged or destroyed by disease, infection or chemotherapy. This process involves transplanting blood stem cells spreading in the bone marrow, where they create new blood cells and promote the growth of new bone marrow. Bone marrow also contains hematopoietic stem cells or immature hematopoietic stem cells called HSC. Most cells are differentiated and can only replicate by themselves. However, because these stem cells are not specialized, they may grow by cell division, maintain stem cells, differentiate into various kinds of blood cells and mature. HSC contained in the bone marrow creates new blood cells throughout your life.

Bone Marrow: Bone marrow contains stem cells, which can develop into various cell types. Common myeloid progenitor stem cells in the bone marrow are precursors of innate immune cells (neutrophils, eosinophils, basophils, mast cells, monocytes, dendritic cells, macrophages) - these are infectious An important front-line responder. Common lymphocyte progenitor stem cells result in adaptive immune cells (B cells and T cells), which are responsible for specific microorganisms based on previous encounters (immune memory). Natural killer (NK) cells are also derived from common lymphoid progenitor cells and are characterized by congenital and adaptive immune cells because they provide direct protection like congenital cells, It can also remain as memory cells. B, T, NK cells are also called lymphocytes