https://www.pcf.org/about-prostate-cancer/diagnosis-staging-prostate-cancer/gleason-score-isup-grade/

An important element of cancer staging is the cancer grade. At the stage of cancer, we will examine the location of the cancer in the body, the function at the macro level, but explain the function at the micro level at the level of how the actual cancer cells look with a microscope To do.

Traditionally, the grade of prostate cancer is described according to the Gleason score, a system named by a pathologist who developed it in the 1960's. Donald Gleason recognized that cancer cells can be divided into five different patterns after being converted from normal cells to tumor cells. Cells were scored on a scale of 1. Cells closest to 1 are considered "lower" tumor cells and tend to appear similar to normal cells. Cells closest to 5 are considered "high grade", and they are mutated to the extent that they are almost different from normal cells.

The pathologist who sees the biopsy sample assigns the Gleason rating to the most prevalent pattern of your biopsy and the second Gleason rating to the second most dominant pattern. Example: 3 + Then add the two levels to determine the Gleason score (2 - 10).

In general, cancers with low Gleason scores (2 to 4) tend to be less aggressive, and cancers with higher Gleason scores (7 to 10) tend to be more aggressive.

Even though there are only a few cells, it is important to know whether there are any Gleason 5 rated cells, even though most pathologists will report this. Adding Gleason 5 to biopsy or prostate increases the risk of recurrence

However, as many cases of prostate cancer grow very slowly, the Gleason system does not necessarily convey the risk of these cases. Patients with a score of 6 and 7 do not clearly understand the nature of their particular cancer

In 2014, the International Urological Pathologist Association issued supplemental guidance and revised the grading system for prostate cancer called the ISUP Evaluation Group.

Your doctor may report your score as a Gleason score or an ISUP grade group, but you may receive two scores

The Gleason grading system is used to use samples from prostate biopsy to assess the prognosis of men with prostate cancer. Together with other parameters, it is included in the staging strategy for prostate cancer, predicting prognosis and guiding treatment. Gleason score was given to prostate cancer based on its microscopic appearance. Cancers with higher Gleason scores are more aggressive and have a worse prognosis. The pathological score ranges from 2 to 10. The higher the number, the higher the risk and the higher the death rate.

Prostate cancer has various stages. There are four stages of prostate cancer. Understanding the early symptoms of prostate cancer is absolutely essential as it helps better treat prostate cancer. There are many prostate movements and you can try to protect your prostate gland. Research shows that exercise can improve your overall prostate health. In this part of this article, I will learn about five early warning signs on prostate cancer. The first early warning sign of prostate cancer is difficult to urinate. You may feel that you need to hurry, but you may feel that nothing will come out after a while. There may be situations where stopping or urination is stopped more frequently than usual. Another sign is that it is difficult to quit. You will find it difficult to stop after it is completed, or you might feel that you still need to urinate even after completion