How effective is Edurant to improve the quality of life of HIV-1 infected patients? According to calculations, as of the end of 2012, there were approximately 98,400 adults infected with HIV in the UK, and the proportion of men infected with HIV was significantly higher than in women. HIV stands for human immunodeficiency virus. This is to make them more sensitive to disease and infection by viruses affecting only humans, making their immune system deficient and killing white blood cells.
HIV infection is associated with a wide range of symptoms associated with the infection itself, opportunistic infections and side effects of treatment. By coping with these symptoms you can improve the quality of life and improve compliance with treatment. The most common and painful symptoms are weight loss, anorexia, malaise, nausea, vomiting, anxiety, depression, cough, fever, and difficulty breathing. (6) Like the pain, the root cause of the treatment symptoms can reduce discomfort. On the other hand, if the disease-specific treatment is inadequate, a symptom-specific method is indicated. Table 2 summarizes the treatment of common symptoms
Lymph node hypertrophy is one of the symptoms of stage 1 HIV infection (acute HIV infection). Many acute HIV-infected people have no symptoms or signs before infection. Some people living with HIV show symptoms and signs (primary or acute HIV infection) 2 to 4 weeks after infection.
HIV disease and its treatment are associated with severe pain syndromes that cause morbidity, decreased function, and decreased quality of life. (5) There are many causes of HIV infection, including infection itself, opportunistic infections, AIDS related malignancies and drug toxicity. The estimated prevalence of pain in AIDS patients is 40% to 60%. Data on the prevalence of pain in developing countries is limited, but from the extent of the disease, the use of older, more toxic primary antiretroviral therapy and restriction of access to opioids is unregulated Pain will be a reality for many patients. It is surprising that the most advanced 26 countries use 90% of the world's morphine supply; the remaining 10% are distributed in the developing countries where HIV infection is at the forefront. (11)