How are cancer and mitosis related?

Mitosis is a process of cell growth and division, so please copy yourself. Cancer is simply a disorganized cell division

In cells, mitosis is always tightly controlled. If there is an error in the cell (eg, DNA is defective), the regulatory protein does not allow its division.

In addition, there are several processes that stimulate cell proliferation. For example, if a cell receives a particular signal, they start splitting.

If any of these two processes fail now, it will lead to uncontrolled mitosis and cancer. For example, if the stimulant is not to be stimulated, or if the regulatory protein is not properly regulated, the cell becomes a cancer cell.

This article will focus on the detection of mitosis. This has many challenges facing other nuclear detection tasks as an example motivating. Mitosis is the process by which non-germ cells divide into two genetically identical daughter cells. Mitotic detection on microscope slides is important for analyzing many diseases - for example, pathologists will calculate mitotic events to determine the replication rate of cancer. In particular, mitotic events are usually detected on static hematoxylin and eosin (H & E) stained slides (the first picture in the next section), the work is more difficult than the identification of mitosis in the above GIF I will.

Until recently cancer has been thought to be a collection of diseases characterized by cell division (mitosis) abnormality. This is logical because the most obvious attribute of most cancers is the formation of clumps called tumors and the cancer cells found in tumors are clearly produced by mitosis. But this is only part of the story. Recent evidence suggests that another feature of cancer may be more important: abnormal cell mobility. In fact, this is also apparent from a clinical point of view. A crucial part of most cancers is tumor formation in primary organs - breast cancer in the case of breast cancer, lung cancer in the case of lung cancer - but cancer cells lick other parts of the body and form tumors therein There is a tendency to do. It was recently discovered that cancer cells can get away from the mass and return to the same quality with new vitality.