Hemophilia is an inherited hemorrhagic disease. Hemophilic patients lack coagulation proteins or lack coagulation proteins. Lack or lack of blood clotting factors Bleeding is most common in joints such as knees, elbows, or ankles, but bleeding can occur anywhere in the body. Haemophilia patients are bleeding fast and do not bleed quickly. The severity of haemophilia varies widely. Hemophilia A and hemophilia B are the most common hereditary hemorrhagic diseases. Haemophilia A is observed in 80% of hemophilia patients, lacking or lacking factor VIII.
There are two types of hemophilia: hemophilia A and hemophilia B. Haemophilia A, also known as "classical hemophilia", is caused by the deficiency of factor VII1. This is the most common form of haemophilia. The second type of haemophilia is hemophilia B, also called "Christmas disease". Hemophilia B is caused by a deficiency of factor IX. Both types of hemophilia are characterized by prolonged bleeding, especially joints, muscles, internal organs, and even cerebral hemorrhage.
According to the National Hemophilia Foundation, the two main types of haemophilia are A and B, the third rare type of hemophilia is called hemophilia C. Each type is a specific factor , That is, directly related to hemophilia. A is Factor VIII deficiency, Hemophilia B is Factor IX deficiency, and Hemophilia C is Factor XI deficiency. A woman inherits two XX chromosomes. One from mother and the other from her father (XX). Male inherits XY chromosome from father (XY). This means that if the son inherits the X chromosome from the mother of hemophilia, he will become haemophilia. However, since women accept two X chromosomes, only the parent with the defective gene will develop the disease.
Men with hemophilia genes on the X chromosome become haemophilia. If there is only one hemophilia gene on the X chromosome, that woman is a "haemophilia vector" and you can pass that gene to your child. Sometimes carriers have low levels of coagulation factors and have symptoms of haemophilia including bleeding. Protein in blood coagulation factor blood stops or suppresses bleeding by platelets. If you or your child has bleeding problems, your doctor asks about your personal and family medical history. This will reveal bleeding problems including you and your family, women and girls. However, some people with haemophilia recently have no family history of this disease.
The National Institute of Cardiopulmonary Blood Research (NHLBI) is leading or sponsors a number of studies for the prevention, diagnosis and treatment of heart, lung, blood, and sleep disorders.
Hemophilia is the most famous hemorrhagic disease. If a person has haemophilia, blood will not coagulate properly and bleeding will persist. Hemophilia patients are called haemophilia patients or bleeding patients. Haemorrhagic diseases such as haemophilia are caused by damage to the thrombosis process in the body. The coagulation process includes platelets and plasma proteins called coagulation factors. Coagulation begins when platelets adhere to the site of vascular injury. There is no protein in plasma that coagulates blood