Hemophilia

Hemophilia is the most common inherited hemorrhagic disease. There are two types of haemophilia, A and B (Christmas disease). Because there is little or no blood protein required for coagulation, it leads to both. Haemophilia A patients lack blood clotting protein, factor VIII, and hemophilia B deficient factor IX. The normal amount of clotting factor in severe hemophilia patients is 1% or less - factor VIII (8) or factor IX (9). People without hemophilia have 50 to 150% of normal levels of factor VIII or factor IX.

According to the National Hemophilia Foundation, the two main types of hemophilia are A and B. A is Factor VIII deficiency, Hemophilia B is Factor IX deficiency, and Hemophilia C is Factor XI deficiency. A woman inherits two XX chromosomes. One is from her mother and the other is a chromosome from her father (XX). Male inherits XY chromosome from father (XY). This means that if the son inherits the X chromosome from the mother of hemophilia, he will become haemophilia. However, since women accept two X chromosomes, only the parent with the defective gene will develop the disease.

Men with hemophilia genes on the X chromosome become haemophilia. If there is only one hemophilia gene on the X chromosome, that woman is a "haemophilia vector" and you can pass that gene to your child. Sometimes carriers have low levels of coagulation factors and have symptoms of haemophilia including bleeding. Protein in blood coagulation factor blood stops or suppresses bleeding by platelets. If you or your child has bleeding problems, your doctor asks about your personal and family medical history. This will reveal bleeding problems including you and your family, women and girls. However, some people with haemophilia recently have no family history of this disease.

The National Institute of Cardiopulmonary Blood Research (NHLBI) is leading or sponsors a number of studies for the prevention, diagnosis and treatment of heart, lung, blood, and sleep disorders.

Hemophilia is the most famous hemorrhagic disease. If a person has haemophilia, blood will not coagulate properly and bleeding will persist. Hemophilia patients are called haemophilia patients or bleeding patients. Haemorrhagic diseases such as haemophilia are caused by damage to the thrombosis process in the body. The coagulation process includes platelets and plasma proteins called coagulation factors. Coagulation begins when platelets adhere to the site of vascular injury. There is no protein in plasma that coagulates blood