Hemophilia

Haemophilia is a rare hereditary blood clotting disorder that occurs mainly in men. Haemophilia patients are deficient or deficient in one of the naturally occurring blood clotting proteins in the blood. The two most common forms of haemophilia are A and B. In people with hemophilia A (also known as a typical hemophilia), factor VIII does not exist in sufficient or nonexistent amounts. In people with hemophilia B (also known as Christmas disease), Factor IX does not exist in sufficient or nonexistent amounts.

According to the National Hemophilia Foundation, the two main types of hemophilia are A and B. A is Factor VIII deficiency, Hemophilia B is Factor IX deficiency, and Hemophilia C is Factor XI deficiency. A woman inherits two XX chromosomes. One is from her mother and the other is a chromosome from her father (XX). Male inherits XY chromosome from father (XY). This means that if the son inherits the X chromosome from the mother of hemophilia, he will become haemophilia. However, since women accept two X chromosomes, only the parent with the defective gene will develop the disease.

Men with hemophilia genes on the X chromosome become haemophilia. If there is only one hemophilia gene on the X chromosome, that woman is a "haemophilia vector" and you can pass that gene to your child. Sometimes carriers have low levels of coagulation factors and have symptoms of haemophilia including bleeding. Protein in blood coagulation factor blood stops or suppresses bleeding by platelets. If you or your child has bleeding problems, your doctor asks about your personal and family medical history. This will reveal bleeding problems including you and your family, women and girls. However, some people with haemophilia recently have no family history of this disease.

The National Institute of Cardiopulmonary Blood Research (NHLBI) is leading or sponsors a number of studies for the prevention, diagnosis and treatment of heart, lung, blood, and sleep disorders.