Genomics

Genomics genomics is the function of genes and DNA in graduate students such as position, structure, arrangement, regulation, function. The genome provides a list of building materials for proteins. (Kerns / McDonald, 2001) Today, scientists are working on identifying each gene of human DNA and sequences of chemical base pairs that make up each gene. This is not an easy task, but in the next few years the world will recognize that the genome is the most important thing since the sliced ​​bread.

Principle of operation: SNP genotyping identifies about 0.1% of the entire genome; total exosome group accounts for about 1%. Whole genome sequencing (or WGS) identifies 100% of the genome - this is the same achievement as the Human Genome Project 13 years and $ 3 billion. Thanks to dramatic advances in sequencing technology, approximately 3 billion A, C, G, T base pairs in the genome can be read in less than a few dollars through Veritas and other services in just a few days. The church was created in 2014

Genomics is a study of the whole genome of living organisms, combining elements of genetics. Genomics uses a combination of recombinant DNA, DNA sequencing and bioinformatics for sequencing, assembling and analyzing the structure and function of the genome. It differs from "classical genetics" in that it takes into account the complete complement of the genetic material of the organism, not one gene at a time or one gene product at a time. In addition, genomics focuses on interactions between loci and alleles in the genome, and other interactions such as polyploidy, pleiotropic expression, hybrid vigor (Fig. 1.1). Genomics takes advantage of the availability of intact DNA sequences throughout the organism and accomplishes this through innovative research by Fred Sanger and the latest generation next-generation sequencing technology.

While the main areas of genomics are still sequencing the genome of various organisms, genome-wide knowledge opens up the possibility of functional genomics, mainly including patterns of gene expression under various conditions. The most important tools here are microarray and bioinformatics. Structural genomics attempts to describe the three-dimensional structure of each protein encoded by a given genome. This genome-based approach allows high throughput structure determination methods by a combination of experimental and modeling methods. The main difference between structural genomics and traditional structural prediction is that structural genomics attempts to determine the structure of each protein encoded by the genome, rather than focusing on specific proteins.