Gene Therapy and its Potential to Cure Deafness

The potential of gene therapy and its hearing loss treatment has lost the important meaning of making life more difficult. Gene therapy replacing defective genes with genetic engineering can treat hearing loss. Yashimo Raphael intentionally tested the gene Atoh 1, which is said to replace guinea pigs and hair cells lost in the inner ear. He discovered that hair cells grew but were incomplete. A few weeks later, the guinea pig disappeared almost completely when I heard the small help of this gene.

Gene therapy is expected to treat many diseases and treatments just recently emerged. It is possible to eliminate and prevent hereditary diseases such as cystic fibrosis and hemophilia and use them as a treatment for heart disease, AIDS, and cancer. Our genes will help us to be unique. Those inherited from their parents do a lot of work to judge our physical characteristics such as eye color, hair color and texture. They also determined the amount of oxygen carried in the blood, and the possibility of some sickness, whether the baby is male or female.

Gene therapy is a technique used to correct defective genes that cause disease progression. In the future, gene therapy may provide a means to treat genetic disorders such as severe combined immunodeficiency disease, cystic fibrosis, and even haemophilia A. Because these diseases are caused by mutations in the DNA sequence of specific genes, gene therapy experiments have used viruses to deliver unmutated copies of these genes to the patient's cells. Gene therapy has been successful in the laboratory. However, some problems with viral gene therapy must be overcome before being widely used. The immune response to the virus not only prevents the delivery of the gene to the target cell, it can also cause severe complications in the patient. In the early gene therapy trial in 1999, this led to the death of Jesse Gelsinger using adenoviral vectors for treatment.

Many of the diseases seen today are the result of defective genes in the patient's DNA and can not be cured by traditional methods such as antibiotics and antiviral drugs. The victim is currently seeking gene therapy as a potential solution to this problem. Gene therapy is the process of replacing defective genes in patient DNA with practical genes that produce the correct gene product. Genetic diseases in which a single known gene such as sickle cell anemia does not function properly are most suitable for gene therapy treatment. There are two types of gene therapy for treating these diseases: patient treatment and embryotherapy.