Finding the End to Genetic Diseases

The heritage of America is very diverse. There is no race of "Americans". Americans are multicultural cultures that have been integrated for generations. Due to the fusion of this culture, genes are mixed. In the past, genes were not fully understood. It was my first time to find out why different plants of the same species had different characteristics before Mendel experimented and understood plants. His goal is to find the key to unravel the mystery of heritage (Copeland and Hammer 12). After years of data collection, he unlocked the door.

Medical genetics attempts to understand how genetic variation is related to human health and disease. When looking for unknown genes that may be related to disease, researchers often use genetic linkage and genetic strain maps to find the location of disease related genomes. At the population level, researchers used Mendel randomization to locate disease-related locations within the genome. This is a particularly useful method for polygenic traits that are not clearly defined for single genes. When candidate genes are found, the corresponding (or homologous) genes of model organisms are typically further investigated. In addition to studying genetic diseases, increased availability of genotyping methods has led to the field of pharmacogenetics: how genotypes affect drug response

Gene therapy is one of the most important advantages of human genetic engineering. Over the past decade, gene therapy has succeeded in finding ways to treat specific heart diseases. Researchers want to find ways to treat all hereditary diseases. This will lead to healthier and evolved people

Although gene therapy works wonders on hereditary disorders, the details surrounding CML does not apply to most common cancers we face today (breast cancer, colorectal cancer, prostate cancer). CML is an inherited disorder caused almost exclusively by chromosomal disorder during cell proliferation. Typically, when cells divide, they provide exactly the same chromosome for each new cell. However, in CML, one chromosome 9 ends with chromosome 12, and vice versa. Named after the city found, it is called the "Philadelphia chromosome". In fact, all CML patients have this Philadelphia chromosome, and it became clear in 1960 that this genetic abnormality leads to cancer.

Ferran-McDermid syndrome or deletion of chromosome 22q13 is a genetic disease considered a rare disease. In most cases, it is caused by loss of genetic material at the end of chromosome 22. This loss occurs during cell division and some of them are destroyed and lost when chromosomes are placed and replicated. A common feature that is affected is the deletion or mutation of the gene SHANK3 (they are like phrases constituting chapters). The absence of this gene means that the affected people suffer from stunts in many areas, especially in terms of speaking ability. This mutation usually occurs spontaneously, ie, it is not genetic.