Experimenting with Aspirin

The purpose of this experiment is to be able to prepare several simple organic compounds, namely aspirin, and also to be able to purify recrystallized compounds. There are four main procedures in this experiment: firstly prepare aspirin, secondly recrystallize aspirin, thirdly measure the melting point of aspirin and finally aspirin discarded from the provided waste container Discard the items. Since the melting point of recrystallized aspirin is within the temperature range 129.3 ° C. to 133.2 ° C. this indicates that the recrystallized aspirin is not as pure as the normal melting point of aspirin at 137 ° C.

In this experiment, aspirin is synthesized by reacting acetic anhydride with salicylic acid in the presence of phosphoric acid. The reaction formula is as follows. After synthesis, the sample is refined by recrystallization. The purity of the sample was then analyzed using TLC. The results section shows all the numerical data (synthesis of aspirin mass, theoretical yield, yield and error rate, and TLC analysis) required for this experiment. After synthesis and analysis, it is decided whether crude oil and recrystallized sample consist of salicylic acid, acetylsalicylic acid, or a combination of the two.

The purpose of this experiment is to make it possible to understand and implement the synthesis of aspirin, to understand the technique for recrystallization and the technique for melting point determination. The main procedure is to prepare aspirin, recrystallize aspirin and finally determine the melting point of aspirin. In order to prepare aspirin, acetic anhydride is added to the measured amount of salicylic acid. Sulfuric acid was added and heated for a short time to complete the reaction. After adding cold water, the water was removed by heating and suction filtration was carried out. For recrystallization of aspirin, the collected crude product prepared as impure aspirin was dissolved in ethanol and hot distilled water was added to the solution. The watch plate was weighed together with the filter paper and suction filtered using the weighed filter paper. Next, please use the equipment necessary to determine the melting point of aspirin

The two main objectives in this lab are the synthesis and analysis of aspirin. There are several ways to synthesize aspirin, but in this experiment, acetic anhydride and salicylic acid are reacted in the presence of phosphoric acid acting as a catalyst. The reaction formula is as follows. You will carry out two tests against your composition to make sure that you actually made aspirin and determined its relative purity. First, measure the melting point of the product sample. Next, test the absorbance of aspirin using a colorimeter or spectrometer and paint it with a solution of iron to color it.