Effect of Glucose Levels on the Brain

It accounts for only 2% of the body weight, but since the brain uses about 75% of the blood glucose, it is today the most expensive organ in the body (Dunbar, 1998; Kahn, 2005). Glucose (the main type of sugar in blood) is the main energy source of the brain and other parts of the body. When the glucose level is high, excess glucose is converted as glycogen and stored, which can then be metabolically returned to glucose and used for energy.

Brain functions such as thought, memory, learning, etc. are closely related to blood glucose level and the way the brain uses this fuel source effectively. For example, if there is not enough glucose in the brain, chemical messengers in the brain do not produce neurotransmitters and communication between the neurons collapses. In addition, hypoglycemia is a common complication of diabetes caused by low levels of glucose in the blood, which can lead to loss of brain function and is associated with inattention and cognitive function.

Glucose homeostasis is important for human health because of the importance of glucose as an energy source and the fact that brain tissue can not synthesize it. Therefore, maintaining adequate glucose levels in the blood is vital to survival. Inappropriate glucose levels in the blood, on the other hand, are the major symptoms of diabetes, and diabetes is the major degenerative disease in society. Normal glucose homeostasis is maintained mainly by glucagon and insulin. After Banting and Best (1921) found insulin in the pancreas and found it capable of lowering blood glucose levels under normal and diabetic conditions, Kimball and Murlin (1923) presented a second factor to raise blood glucose levels in the pancreas I found out. Glucagon

Hypoglycemic glucose is a natural sugar which is the main fuel used by the brain. Glucose production is regulated primarily by the pancreas in response to chemical messages from the brain called the hypothalamus. When the hypothalamus feels that the glucose level is too high or too low it sends a chemical order to the pancreas to reduce or increase glucose production by adjusting the amount of insulin released into the blood system . For most people, this feedback adjustment process helps keep brain glucose at a very stable level. Some people have difficulty stabilizing brain glucose levels for various reasons. These people are said to be hypoglycemic. Rapid fluctuations in intracerebral glucose may lead to temporary confusion of thought and emotion The most common symptoms are confusion, carelessness, and irritability.