People with Down's syndrome are the first of all humans with physical features to be distinguished because chromosome 21 has been added. The estimated incidence of Down's syndrome is 1 in 1 to 1,000 out of 1,100 births. Due to this chromosomal aberration, approximately 3,000 to 5,000 children are born every year. Approximately 250,000 families in the United States are considered to suffer from Down's syndrome. Down syndrome children are usually small, physical and mental development is slower than young people without Down syndrome.
Down syndrome is an increasingly common disease in the United States. This is an inherited disorder caused by extra chromosome 21. One in 800 births is Down Syndrome (National Down Syndrome Association). Down syndrome is the most common form of identifiable delay (Ludman and Wynbrandt, p. 23) and genetic disease (National Down Syndrome Association). Down syndrome was initially thought to be a disease by John Langdon Down in 1866 and is called "father" of Down syndrome with the same name as Down. The original name of Down's syndrome was "a fool of Mongolia" due to the inclination of the eyes and a flat face (National Down Syndrome Association). He thinks this is a counterattack against Mongolian ancestors, but that word is now considered to be outdated and aggressive. But centuries ago, the characteristics of Down's syndrome were discovered in art, literature and science (National Down Syndrome Association).
Down Syndrome, formerly known as the "Mongolian", is characterized by the characteristics of a person with Down's syndrome that resembles Mongolian Asians. Down syndrome occurs to about 1 in about 800 newborns around the world. When a person inherits all or part of an extra copy of chromosome 21, it causes Down's syndrome. For unknown reasons, this can happen in various ways. The most common chromosomal abnormalities that cause Down's syndrome (about 95% of all cases) are trisomy 21, a defect in which there is an additional third copy of chromosome 21 in all cells in the body. 21 The risk of trisomy is directly related to the age of the mother. For an 18-year-old mother, the number of births of Down's syndrome is relatively small, and about 2 out of 2,100 newborns are born. In the late birth, the risk has increased significantly - from the birth of 1000 people of a 30 year old woman to one of 100 women of a 40 year old woman