Down Syndrome

Down's syndrome Down's syndrome is one of the most frequently occurring chromosomal abnormalities in humans and affects people of all ages, races, and economic levels. It is a chromosomal abnormality in the development of cells and allows people to have 47 chromosomes at birth instead of 46 normal chromosomes. People with Down's syndrome may have mild to severe learning and physical symptoms, including small skulls, extra folds under the eyes, and prominent tongue.

Mosaic is the least common form of Down's syndrome, accounting for only about 1% of all Down's syndrome cases. Studies have shown that Down's syndrome may be less characterized by Down syndrome than other types of Down's syndrome patients. However, people with Down Syndrome have broad capabilities and can not be generalized. In translocation, the total number of intracellular chromosomes is still 46 in about 4% of cases of Down's syndrome; however, extra whole or part of the copy of chromosome 21 is bound to another chromosome, usually chromosome 14 doing. The presence of all or a portion of chromosome 21 additionally leads to a distinguishing feature of Down's syndrome.

In Down's syndrome Down's syndrome, one is born with an extra copy of chromosome 21. And it is one of 23 human chromosomes. Scientists do not know why Down Syndrome is at high risk of Alzheimer's disease, but it may be associated with extra copies of chromosome 21. This chromosome contains the gene encoding APP, which is excised into beta-amyloid fragment in Alzheimer's disease and accumulates in plaques. Extra copies of chromosome 21 increase the number of beta-amyloid fragments in the brain

Many people with Down's syndrome develop Alzheimer's disease. The symptoms and signs of Alzheimer's disease often appear 10 to 20 years earlier than people with Down's syndrome. Genes contained in extra chromosomes that cause Down's syndrome markedly increase the risk of Alzheimer's disease. These risk factors are also associated with vascular dementia, which is a type of dementia caused by damaged blood vessels in the brain. Cooperating with your medical team to plan to manage these factors will help protect your heart - and may also help reduce the risk of Alzheimer's disease and vascular dementia Hmm

Down syndrome is a lifelong disease. Infants and children with Down's syndrome help to improve the physical and intellectual abilities of infants and children. Most of these services focus on helping children with Down's syndrome get the full potential. These services usually include language, occupation, and physical therapy provided through the state's early intervention program. Although many children are included in regular classes, children with Down Syndrome may also need additional assistance or attention at school.