Everyone with Down Syndrome is made of cells. Each cell has a specific DNA containing genetic material that constitutes a human being. Genes are the cause of our appearance and features. Of course, the cell consists of 23 chromosomes. Whenever a person has an extra copy of chromosome 21, this person will be Down Syndrome. "It is this additional genetic material that causes the physical features and hypoplasia associated with DS" ("Down's syndrome"). It can be inherited from one or both parents.
Regardless of the type of down syndrome in humans, all key components of chromosome 21 are present in all or part of the cells of patients with Down's syndrome. This additional genetic material alters the developmental process and results in features related to Down's syndrome. The cause of additional complete or partial chromosomes is yet to be determined. The age of the mother is the only factor related to the increasing potential of infants with Down's syndrome who are neither segregating nor mosaicing. However, due to the high birth rate of young women, 80% of children with Down's syndrome are born to women under the age of 35.
Patients with Down's syndrome tend to decrease with age, and usually begin to decline from around 50 years old. Down's syndrome is also associated with Alzheimer's disease, an increased risk of brain disease leading to progressive loss of memory. Approximately half of adults with down-sick syndrome are suffering from Alzheimer's disease. Alzheimer's disease is usually a disease occurring in elderly people, Down's syndrome usually develops this disease at age 50 or 60 years.
Many people with Down's syndrome develop Alzheimer's disease. The symptoms and signs of Alzheimer's disease often appear 10 to 20 years earlier than people with Down's syndrome. Genes contained in extra chromosomes that cause Down's syndrome markedly increase the risk of Alzheimer's disease. These risk factors are also associated with vascular dementia, which is a type of dementia caused by damaged blood vessels in the brain. Cooperating with your medical team to plan to manage these factors will help protect your heart - and may also help reduce the risk of Alzheimer's disease and vascular dementia Hmm