Cystic Fibrosis or Mucoviscidosis

Cystic fibrosis Cystic fibrosis, also known as mucous mucus, is a dysfunctional and fatal genetic disorder that inherits autosomal recessive inheritance (OMIM # 219700). This disease is fatal at 2 years of age without treatment and it is the most common deadly inherited disease in childhood. Today, through treatment, patients can survive for more than 25 to 30 years. In the American white population, CF has an average frequency of 1 in the birth of 2000. The frequency of other races (human genetics) is quite low.

Cystic fibrosis also known as mucous mucus is the result of a single defective gene appearing on the chromosome. It is a life-threatening genetic disease, which means that it is not acquired, and people are born with it. Cystic fibrosis is autosomal recessive; this means that in order for a person to have cystic fibrosis it must have two copies of the wrong gene. Only one person carrying a copy of the cystic fibrosis gene is called a vector and has no symptoms. Usually this person does not know that they are operators

Cystic fibrosis is an autosomal recessive disorder - that is, two defective genes (one for each parent) are needed to develop the disease. The gene thought to cause cystic fibrosis is called cystic fibrosis transmembrane conductance regulator or CFTR. This gene is on chromosome 7. The severity and extent of this disease vary widely among patients with cystic fibrosis. Typically, this condition results in an increase in the chloride transport defect and trauma across epithelial cells and the viscosity of body secretions, particularly secretions from the respiratory tract (ie, the lungs, throat) and pancreas. As a result, patients are prone to pancreatic dysfunction and repeated chest infections

Cystic fibrosis, also known as mucous mucus, is an autosomal recessive disorder affecting mainly the lung, pancreas, liver and intestine. It is characterized by abnormal transport of chloride and sodium in epithelial cells, resulting in a viscous, viscous secretion. One in every 25 people has this defective gene. For children, this situation may weaken the body.

About 1 Caucasian of 201 hold at least one fatal defective gene (in Europe) that causes cystic fibrosis, CF or myxofibrosis, but that carrier does not show signs of disease . As a result, 10 million people have defective genes, they do not know about it. Therefore, it is one of the most common genetic defects in the United States. Cystic fibrosis is an autosomal recessive gene. This means that it is possible, but you do not have to skip over generations. To be affected by this disease, both parents must be carriers. If one parent suffers from cystic fibrosis and the other is not a carrier, the child has a 100% chance of being a carrier. If one parent has cystic fibrosis and the other is a carrier, that child has a 50% chance of having CF and a 50% chance of being a carrier. If parents are carriers, 25% of children will be CF, the chances of becoming carriers will be 50%, 25% of the possibilities will not be affected at all.