Curing Blindness in Mice

Human eyes are complex organs composed of various parts, each of which has a unique function. A part of the eyes detects the light and sends this information to various other parts of the eye. Ultimately, the signal is sent to the brain itself, which is visible to the person. If any part of the chain does not work properly, human eyesight will be compromised. The retina is an important part of the eye. The task is to pass the information to the various cells in the eye, and ultimately to the brain, after detecting the light.

So far, much of this work is theoretical, but some researchers are approaching the 'treatment' era. Last year, the Salk Institute announced a study called "aging can be reversible" based on experiments by researchers with early aging with mice that led to premature aging. By giving mice antibiotics, researchers can genetically engineer them to "open" the four genes associated with aging. The average life expectancy of the mouse is extended by 30%, and normally processed mice seem to aging in order

Using a mouse, researchers at the University of California, Los Angeles found that the missing gene in infants born with blind disease is called Leber's congenital black sputum and is an important enzyme for vision did. The nature of this enzyme has been a mystery for scientists for a long time. The results of this study are expected to treat certain congenital blindness through gene therapy. Many of these ongoing studies involve the use of mice with genetic mutations. Hutchinson - Gilford Progeria syndrome, also known as premature aging or HGPS, is a rare and deadly hereditary disorder characterized by accelerated aging and cardiovascular disease in children. UCLA researchers used a mouse model that strictly reflects genetic defects in many human syndrome cases and that experimental drugs improve bone density, reduce bone fractures, increase body weight, and develop disease I found that it helps to delay. Based on the research results, researchers can start to treat children and consider examining clinical trials in humans.

Bennett and Maguire started working on congenital blindness by working with mice and dogs. They reported in 2001 that they and other scientists improved the sight of the three blind dogs with genetic diseases of the dogs and allowed them to go through a dark obstacle path. The couple adopted two dogs, a pair of mother and child named Venus and Mercury.