Can daily use of macrolides decrease the onset of COPD exacerbations?

The use of macrolide every day decreases the incidence of acute exacerbation of COPD The fourth most common cause of death in the United States is chronic obstructive pulmonary disease ("chronic obstructive pulmonary disease", 2010). Many patients with COPD are suffering from chronic exacerbation, which leads to poor quality of life and undesirable outcomes. The treatment of acute exacerbation of COPD is controversial. Some experts believe that the use of antibiotics during the degradation period will help eradicate infectious agents, others believe that continued use of antibiotics may cause microbial tolerance.

Introduction: COPD exacerbations can be defined as events in the natural history of diseases characterized by changes in baseline respiratory distress, cough and / or sputum of patients who exceed normal daily changes and can be used for obstructive pulmonary disease According to GOLD, patients with COPD may need to change their medicine The deterioration of COPD itself is weakened The harm they give to the body of a patient is a physical disorder It may even lead to death Precautions may eventually help the patient avoid COPD worsening

Chronic obstructive pulmonary disease (COPD) is a slowly developing respiratory disease. It is characterized by shortness of breath, pain, and latent onset of limited function 2 and is exacerbated by worsening.

Patient's perception of severe COPD and mortality shift: qualitative research identifies milestones and important development opportunities

Patients with asthma and chronic obstructive pulmonary disease (COPD) usually have shortness of breath. However, during the course of these diseases, patients often describe chest tightness, which can sometimes be interpreted as chest pain. In some cases, this may be related to pneumonia. For efficient transportation of the esophagus from the mouth to the stomach, a cooperative and continuous movement pattern is required to extrude food from above and remove backflow of acid and bile from below. Esophageal Disorders Interruption of this highly integrated process, often referred to as PEMD, can cause discomfort (dysphagia) and chest pain when swallowed (19).

COPD may be mild or severe. COPD is progressive. Over time, breathing worsened rapidly. Exercise becomes more difficult, even everyday activities become difficult. COPD may also cause cough, chest tightness, wheezing, chronic cramps (or mucus). Severe illness can lead to weight loss and fatigue. Depression, thin bone, lung cancer, heart disease, muscle weakness are more common in COPD patients. It can also cause severe disability and even even death. COPD spends 50 billion US dollars annually on wage losses and medical expenses. That is the third most common cause of death. In the United States, 24 million people suffer from chronic obstructive pulmonary disease and half do not know it. Cessation of smoking slows the progress of lung disease