Bovine Spongiform Encephalopathy

Bovine spongiform encephalopathy (BSE) is a relatively new disease mainly found in cattle. This cattle disease was seen by histopathological examination of the brain first affected in the UK in November 1986 (Kimberlin, 1993). For the first time in the period from 1986 to 1990, this disease developed into a massive epidemic in the majority of the UK and caused serious economic consequences (Moore, 1996). BSE occurs mainly in adult cattle with different gender gender.

The term BSE is short but it represents bovine spongiform encephalopathy with a long name. "Cattle" means that the disease affects the cow, "sponge" means that the brain of the diseased cow looks like a sponge under the microscope, "encephalopathy" is a disease of the brain It means there is. Mad cow disease is often called "mad cow disease." Most scientists believe that mad cow disease is caused by a protein called a prion protein. Normal prion proteins become harmful abnormal prion proteins for reasons that are not well understood. The sick cow's body does not even know that there is an abnormal prion. I do not know where it is, the bull's body can not resist disease.

Bovine spongiform encephalopathy (BSE), commonly known as "mad cow disease", is a member of a family of prion diseases or infectious spongiform encephalopathies. After the first mad cow disease in Britain occurred in 1987, it was found that mad cow disease and a new human disease (variant Creutzfeld-Jakob disease) and animals (cat spongiform encephalopathy, extrinsic ungulatory encephalopathy, Spirit) Spongiform encephalopathy of longevity animals Prions are unique infectious agents that bring physicians unique challenges. This discussion will focus on the nature of prion, the factors that cause the epidemic of mad cow disease, the influence on the treatment of suspected CJD patients, and the efforts to limit drug diffusion.

CWD is a contagious spongiform encephalopathy and belongs to the same type of disease as bovine spongiform encephalopathy (BSE - commonly referred to as "mad cow disease"). These diseases are caused by prion, which is an infectious protein. These diseases affect the brain and spinal cord, causing symptoms such as weakness, discordance, abnormal behavior. It is not fully understood how CWD is transmitted from animals to animals, but it is transmitted by direct contact between animals and animals, or when eating animal contaminated with saliva or stool of infected animals It is thought. It shows the path from Moose to Moose.

Infectious agents composed of prion viruses and proteins are unique in that they are associated with certain forms of neurodegenerative diseases. Bovine spongiform encephalopathy (BSE, or "mad cow disease") is a bovine prion disease associated with human mutant Creutzfeldt-Jakob disease (vCJD). Consumption of cattle products, including certain hazardous substances such as brain tissue, is the most likely route for prions to spread to humans. Natural toxins include mycotoxins, marine organism toxins, toxins from cyanoglucosides, poison mushrooms, and the like. Staple foods such as corn and cereal may contain high levels of mycotoxins such as aflatoxin and ochratoxin produced by grain molds. Long-term exposure can affect the immune system and normal development and can cause cancer