Biologically Tissue Engineered Blood Vessel

Introduction Tissue Engineering Vessels (TEBV) usually require synthetic or modified biomaterials to obtain support, strength and anchorage effects. However, this new method involves the use of cultured human cells, which means that synthetic materials or materials from outside the body are not used. Designing organs and successfully transplanting organs can mean further progress in making larger organs such as the liver and kidneys, so this is a scientific advancement. Currently, patency of synthetic vascular grafts transplanted into patients is very low and increases the risk of thrombosis (L'heureux et al., 1998).

In biochemistry, tissue engineering involves many applications, which are suitable for replacing and repairing tissue, as well as blood vessels, bladder, bone and cartilage. One of the advantages of tissue engineering is that it attempts to perform biochemical functions through different types of cells, especially stem cells, to support an artificially created support system. Briefly, tissue engineering is used to support the performance of artificial pancreas and bioartificial liver. (Ashammakhi et al. 2007)

Although the definition of the majority of tissue engineering covers a wide range of applications, in practice this term is closely related to the use of repair or replacement of a part or whole tissue (ie bone, cartilage, blood vessel, bladder, skin, muscle, etc.) . In many cases, the organizations involved require specific mechanical and structural characteristics to function properly. This term also applies to efforts to perform specific biochemical functions using cells in an artificially generated support system such as artificial pancreas or bioartificial liver. Although the term regenerative medicine is often synonymous with tissue engineering, people involved in regenerative medicine place greater emphasis on the use of stem cells or progenitor cells to produce tissues.

Tissue engineering is the use of cellular, engineering, and materials methods, as well as combinations of suitable biochemical and physicochemical factors to improve or replace biological tissue. Tissue engineering involves the use of tissue scaffolds to form new biological tissues for medical purposes. It has been classified as a subarea of ​​biological material, but as its scope and importance increases it can be regarded as an independent field. Although the definition of the majority of tissue engineering covers a wide range of applications, in practice this term is closely related to the use of repair or replacement of a part or whole tissue (ie bone, cartilage, blood vessel, bladder, skin, muscle, etc.) . In many cases, the organizations involved require specific mechanical and structural characteristics to function properly. This term also applies to efforts to use manually created cells within the support system for specific biochemical functions (see, for example,